| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4163796 | 12a | AUC | = | 14.724 | mg/L.hr | ALA4143100 | ng.hr.mL-1 | Rattus norvegicus | |||
| 2. | ALA4163796 | 12a | MRT | = | 2.576 | hr | ALA4143101 | hr | Rattus norvegicus | |||
| 3. | ALA4163796 | 12a | VRT | = | 4.423 | hr2 | ALA4143102 | hr2 | Rattus norvegicus | |||
| 4. | ALA4163796 | 12a | CL(app) | = | 5.433 | L/hr/kg | ALA4143103 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 5. | ALA4163796 | 12a | Vz | = | 6.231 | L/Kg | ALA4143104 | L.kg-1 | Rattus norvegicus | |||
| 6. | ALA4163796 | 12a | beta t1/2 | = | 0.795 | hr | ALA4143105 | hr | Rattus norvegicus | |||
| 7. | ALA4163796 | 12a | Cmax | = | 5.87 | mg/L | ALA4143106 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 8. | ALA4163796 | 12a | IC50 | = | 0.18 | uM | ALA4143036 | 6.75 | nM | Sus scrofa | ||
| 9. | ALA4163796 | 12a | IC50 | = | 1.68 | uM | ALA4143037 | 5.78 | nM | Homo sapiens | ||
| 10. | ALA4163796 | 12a | IC50 | = | 5.69 | uM | ALA4143038 | 5.25 | nM | Homo sapiens | ||
| 11. | ALA4163796 | 12a | IC50 | = | 23.49 | uM | ALA4143039 | 4.63 | nM | |||
| 12. | ALA4163796 | 12a | IC50 | = | 16.52 | uM | ALA4143040 | 4.78 | nM | Homo sapiens | ||
| 13. | ALA4163796 | 12a | IC50 | = | 10.16 | uM | ALA4143045 | 4.99 | nM | Homo sapiens | ||
| 14. | ALA4163796 | 12a | IC50 | = | 31.57 | uM | ALA4143046 | 4.50 | nM | Homo sapiens | ||
| 15. | ALA4163796 | 12a | IC50 | = | 25.97 | uM | ALA4143047 | 4.59 | nM | Homo sapiens | ||
| 16. | ALA4163796 | 12a | IC50 | = | 15.27 | uM | ALA4143048 | 4.82 | nM | Homo sapiens | ||
| 17. | ALA4163796 | 12a | IC50 | = | 19.89 | uM | ALA4143049 | 4.70 | nM | |||
| 18. | ALA4163796 | 12a | IC50 | = | 14.25 | uM | ALA4143050 | 4.85 | nM | Homo sapiens | ||
| 19. | ALA4163796 | 12a | Activity | 0 | ALA4143063 | Dose-dependent effect | Homo sapiens | |||||
| 20. | ALA4163796 | 12a | Activity | = | 24.2 | % | ALA4143064 | % | Homo sapiens |
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