# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4164465 | (+/-)-42 | Vduss | = | 54 | L/Kg | ALA4322936 | L.kg-1 | ||||
2. | ALA4164465 | (+/-)-42 | Vdss | = | 3.2 | L/Kg | ALA4322932 | L.kg-1 | ||||
3. | ALA4164465 | (+/-)-42 | solubility | = | 19 | ug ml-1 | ALA4322929 | ug.mL-1 | ||||
4. | ALA4164465 | (+/-)-42 | fAUC | = | 0.24 | ug.hr/ml | ALA4322962 | ng.hr.mL-1 | ||||
5. | ALA4164465 | (+/-)-42 | Ratio | = | 15 | ALA4322961 | ||||||
6. | ALA4164465 | (+/-)-42 | logD | = | 4.6 | ALA4158464 | ||||||
7. | ALA4164465 | (+/-)-42 | IC50 | > | 10 | uM | ALA4158456 | nM | Homo sapiens | |||
8. | ALA4164465 | (+/-)-42 | IC50 | > | 10 | uM | ALA4158455 | nM | Homo sapiens | |||
9. | ALA4164465 | (+/-)-42 | IC50 | > | 10 | uM | ALA4158454 | nM | Homo sapiens | |||
10. | ALA4164465 | (+/-)-42 | IC50 | > | 10 | uM | ALA4158453 | nM | Homo sapiens | |||
11. | ALA4164465 | (+/-)-42 | IC50 | > | 10 | uM | ALA4158452 | nM | Homo sapiens | |||
12. | ALA4164465 | (+/-)-42 | IC50 | > | 10 | uM | ALA4158451 | nM | Homo sapiens | |||
13. | ALA4164465 | (+/-)-42 | IC50 | > | 10 | uM | ALA4158450 | nM | Homo sapiens | |||
14. | ALA4164465 | (+/-)-42 | IC50 | > | 10 | uM | ALA4158449 | nM | Homo sapiens | |||
15. | ALA4164465 | (+/-)-42 | IC50 | > | 10 | uM | ALA4158448 | nM | Homo sapiens | |||
16. | ALA4164465 | (+/-)-42 | CL free | = | 966 | ml/min.kg | ALA4158444 | mL.min-1.kg-1 | Rattus norvegicus | |||
17. | ALA4164465 | (+/-)-42 | Fu | = | 5.9 | % | ALA4158447 | |||||
18. | ALA4164465 | (+/-)-42 | F | = | 35 | % | ALA4158446 | % | Rattus norvegicus | |||
19. | ALA4164465 | (+/-)-42 | MRT | = | 0.9 | hr | ALA4158445 | hr | Rattus norvegicus | |||
20. | ALA4164465 | (+/-)-42 | CL | = | 58 | ml/min.kg | ALA4158443 | mL.min-1.kg-1 | Rattus norvegicus |