Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA4164465	(+/-)-42	logD	=	4.6		ALA4158464
2.	ALA4164465	(+/-)-42	IC50	>	10	uM	ALA4158456		nM	Homo sapiens
3.	ALA4164465	(+/-)-42	IC50	>	10	uM	ALA4158455		nM	Homo sapiens
4.	ALA4164465	(+/-)-42	IC50	>	10	uM	ALA4158454		nM	Homo sapiens
5.	ALA4164465	(+/-)-42	IC50	>	10	uM	ALA4158453		nM	Homo sapiens
6.	ALA4164465	(+/-)-42	IC50	>	10	uM	ALA4158452		nM	Homo sapiens
7.	ALA4164465	(+/-)-42	IC50	>	10	uM	ALA4158451		nM	Homo sapiens
8.	ALA4164465	(+/-)-42	IC50	>	10	uM	ALA4158450		nM	Homo sapiens
9.	ALA4164465	(+/-)-42	IC50	>	10	uM	ALA4158449		nM	Homo sapiens
10.	ALA4164465	(+/-)-42	IC50	>	10	uM	ALA4158448		nM	Homo sapiens
11.	ALA4164465	(+/-)-42	CL free	=	966	ml/min.kg	ALA4158444		mL.min-1.kg-1	Rattus norvegicus
12.	ALA4164465	(+/-)-42	Fu	=	5.9	%	ALA4158447
13.	ALA4164465	(+/-)-42	F	=	35	%	ALA4158446		%	Rattus norvegicus
14.	ALA4164465	(+/-)-42	MRT	=	0.9	hr	ALA4158445		hr	Rattus norvegicus
15.	ALA4164465	(+/-)-42	CL	=	58	ml/min.kg	ALA4158443		mL.min-1.kg-1	Rattus norvegicus
16.	ALA4164465	(+/-)-42	solubility	=	360	uM	ALA4158442		nM
17.	ALA4164465	(+/-)-42	IC50	=	4	nM	ALA4158441	8.40	nM	Homo sapiens
18.	ALA4164465	(+/-)-42	IC50	=	2.5	nM	ALA4158441	8.60	nM	Homo sapiens
19.	ALA4164465	(+/-)-42	Vduss	=	54	L/Kg	ALA4322936		L.kg-1
20.	ALA4164465	(+/-)-42	Vdss	=	3.2	L/Kg	ALA4322932		L.kg-1