| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4165366 | 4x | Ratio | = | 0.08 | ALA4134173 | ||||||
| 2. | ALA4165366 | 4x | t1/2 | = | 5.23 | hr | ALA4134172 | hr | Mus musculus | |||
| 3. | ALA4165366 | 4x | AUClast | = | 46822 | hr.ng/ml | ALA4134171 | ng.hr.mL-1 | Mus musculus | |||
| 4. | ALA4165366 | 4x | Cmax | = | 9268 | ng/ml | ALA4134170 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 5. | ALA4165366 | 4x | AUClast | = | 4468 | hr.ng/ml | ALA4134169 | ng.hr.mL-1 | Rattus norvegicus | |||
| 6. | ALA4165366 | 4x | Cmax | = | 3563 | ng/ml | ALA4134168 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 7. | ALA4165366 | 4x | t1/2 | = | 0.98 | hr | ALA4134167 | hr | Rattus norvegicus | |||
| 8. | ALA4165366 | 4x | F | = | 57.2 | % | ALA4134166 | % | Rattus norvegicus | |||
| 9. | ALA4165366 | 4x | Ratio | = | 1.05 | ALA4134165 | ||||||
| 10. | ALA4165366 | 4x | Papp | = | 17.5 | 10'-6 cm/s | ALA4134164 | 10'-6 cm/s | ||||
| 11. | ALA4165366 | 4x | Kinetic_solubility | = | 38.9 | uM | ALA4134163 | nM | ||||
| 12. | ALA4165366 | 4x | PPB | = | 99.68 | % | ALA4134162 | % | ||||
| 13. | ALA4165366 | 4x | PPB | = | 99.81 | % | ALA4134161 | % | ||||
| 14. | ALA4165366 | 4x | PPB | = | 99.87 | % | ALA4134160 | % | ||||
| 15. | ALA4165366 | 4x | INH | = | 12.5 | % | ALA4134159 | % | Homo sapiens | |||
| 16. | ALA4165366 | 4x | INH | = | 11.2 | % | ALA4134158 | % | Homo sapiens | |||
| 17. | ALA4165366 | 4x | INH | = | 5.9 | % | ALA4134157 | % | Homo sapiens | |||
| 18. | ALA4165366 | 4x | IC50 | > | 50 | uM | ALA4134156 | nM | Homo sapiens | |||
| 19. | ALA4165366 | 4x | Activity | = | 25.4 | % | ALA4134155 | % | Homo sapiens | |||
| 20. | ALA4165366 | 4x | INH | 0 | ALA4134154 | Not Active | % |
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