| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4166144 | 19 | Therm_solubility | 0 | ALA4322200 | Soluble | ||||||
| 2. | ALA4166144 | 19 | Therm_solubility | 0 | ALA4322199 | Soluble | ||||||
| 3. | ALA4166144 | 19 | Kinetic_solubility | 0 | ALA4322198 | Soluble | ||||||
| 4. | ALA4166144 | 19 | Papp | = | 29 | 10'-6 cm/s | ALA4322187 | 10'-6 cm/s | ||||
| 5. | ALA4166144 | 19 | Papp | = | 24 | 10'-6 cm/s | ALA4322186 | 10'-6 cm/s | ||||
| 6. | ALA4166144 | 19 | IC50 | = | 0.14 | uM | ALA4322185 | 6.85 | nM | |||
| 7. | ALA4166144 | 19 | IC50 | = | 0.8 | nM | ALA4322184 | 9.10 | nM | Homo sapiens | ||
| 8. | ALA4166144 | 19 | Activity | 0 | ALA4150467 | Toxic | Mus musculus | |||||
| 9. | ALA4166144 | 19 | MTD | > | 40 | mg kg-1 | ALA4150501 | mg kg-1 | Mus musculus | |||
| 10. | ALA4166144 | 19 | Activity | 0 | ALA4150499 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
| 11. | ALA4166144 | 19 | Activity | 0 | ALA4150498 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
| 12. | ALA4166144 | 19 | Activity | 0 | ALA4150497 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
| 13. | ALA4166144 | 19 | Activity | 0 | ALA4150496 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
| 14. | ALA4166144 | 19 | Activity | 0 | ALA4150495 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
| 15. | ALA4166144 | 19 | Ratio AUC | = | 0.71 | ALA4150491 | ||||||
| 16. | ALA4166144 | 19 | AUC | = | 11831 | ng/mL.hr | ALA4150490 | ng.hr.mL-1 | ||||
| 17. | ALA4166144 | 19 | AUC | = | 8456 | ng/g.hr | ALA4150489 | ng/g.hr | ||||
| 18. | ALA4166144 | 19 | Activity | 0 | ALA4150488 | Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
| 19. | ALA4166144 | 19 | Activity | 0 | ALA4150487 | Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
| 20. | ALA4166144 | 19 | Activity | 0 | ALA4150486 | Toxic | Salmonella enterica subsp. enterica serovar Typhimurium |
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