Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4168811	3; KBP-7018	IC50	=	1600	nM	ALA4136260	5.80		nM	Homo sapiens
2.	ALA4168811	3; KBP-7018	IC50	=	25	nM	ALA4136261	7.60		nM	Homo sapiens
3.	ALA4168811	3; KBP-7018	IC50	=	110	nM	ALA4136262	6.96		nM	Homo sapiens
4.	ALA4168811	3; KBP-7018	IC50	=	100	nM	ALA4136263	7.00		nM	Mus musculus
5.	ALA4168811	3; KBP-7018	IC50	>	30	nM	ALA4136264			nM	Homo sapiens
6.	ALA4168811	3; KBP-7018	INH	=	91	%	ALA4136271			%	Homo sapiens
7.	ALA4168811	3; KBP-7018	INH	=	88	%	ALA4136274			%	Homo sapiens
8.	ALA4168811	3; KBP-7018	INH	=	91	%	ALA4136277			%	Homo sapiens
9.	ALA4168811	3; KBP-7018	INH	=	87	%	ALA4136278			%	Homo sapiens
10.	ALA4168811	3; KBP-7018	INH	=	99	%	ALA4136280			%	Homo sapiens
11.	ALA4168811	3; KBP-7018	t1/2	=	4.3	hr	ALA4136285			hr	Mus musculus
12.	ALA4168811	3; KBP-7018	t1/2	=	4.8	hr	ALA4136286			hr	Rattus norvegicus
13.	ALA4168811	3; KBP-7018	t1/2	=	3.3	hr	ALA4136287			hr	Canis lupus familiaris
14.	ALA4168811	3; KBP-7018	AUC	=	17004	hr.ng/ml	ALA4136288			ng.hr.mL-1	Mus musculus
15.	ALA4168811	3; KBP-7018	AUC	=	6406	hr.ng/ml	ALA4136289			ng.hr.mL-1	Rattus norvegicus
16.	ALA4168811	3; KBP-7018	AUC	=	2964	hr.ng/ml	ALA4136290			ng.hr.mL-1	Canis lupus familiaris
17.	ALA4168811	3; KBP-7018	F	=	51	%	ALA4136291			%	Mus musculus
18.	ALA4168811	3; KBP-7018	F	=	68	%	ALA4136292			%	Rattus norvegicus
19.	ALA4168811	3; KBP-7018	F	=	29	%	ALA4136293			%	Canis lupus familiaris
20.	ALA4168811	3; KBP-7018	Activity		0		ALA4136294		Dose-dependent effect		Mus musculus