# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4169575 | 4bq | IC50 | = | 10.5 | uM | ALA4134825 | 4.98 | nM | Homo sapiens | ||
2. | ALA4169575 | 4bq | Activity | 0 | ALA4134824 | Not Active | Mus musculus | |||||
3. | ALA4169575 | 4bq | Activity | 0 | ALA4134823 | Active | Mus musculus | |||||
4. | ALA4169575 | 4bq | F | = | 45.4 | % | ALA4134822 | % | Rattus norvegicus | |||
5. | ALA4169575 | 4bq | CL | = | 4.6 | ng.hr/ml | ALA4134821 | ng.hr/ml | Rattus norvegicus | |||
6. | ALA4169575 | 4bq | t1/2 | = | 10.8 | hr | ALA4134820 | hr | Rattus norvegicus | |||
7. | ALA4169575 | 4bq | t1/2 | = | 7.2 | hr | ALA4134819 | hr | Rattus norvegicus | |||
8. | ALA4169575 | 4bq | MRT | = | 5.1 | hr | ALA4134818 | hr | Mus musculus | |||
9. | ALA4169575 | 4bq | MRT | = | 5.8 | hr | ALA4134817 | hr | Rattus norvegicus | |||
10. | ALA4169575 | 4bq | MRT | = | 5.5 | hr | ALA4134816 | hr | Rattus norvegicus | |||
11. | ALA4169575 | 4bq | AUC | = | 243.7 | ng.hr/ml | ALA4134815 | ng.hr.mL-1 | Mus musculus | |||
12. | ALA4169575 | 4bq | AUC | = | 432.2 | ng.hr/ml | ALA4134814 | ng.hr.mL-1 | Rattus norvegicus | |||
13. | ALA4169575 | 4bq | AUC | = | 889.1 | ng.hr/ml | ALA4134813 | ng.hr.mL-1 | Rattus norvegicus | |||
14. | ALA4169575 | 4bq | AUCt | = | 188.3 | ng.hr/ml | ALA4134812 | ng.hr.mL-1 | Mus musculus | |||
15. | ALA4169575 | 4bq | AUCt | = | 363.6 | ng.hr/ml | ALA4134811 | ng.hr.mL-1 | Rattus norvegicus | |||
16. | ALA4169575 | 4bq | AUCt | = | 824.6 | ng.hr/ml | ALA4134810 | ng.hr.mL-1 | Rattus norvegicus | |||
17. | ALA4169575 | 4bq | Cmax | = | 113.1 | ng/ml | ALA4134809 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
18. | ALA4169575 | 4bq | Cmax | = | 114.4 | ng/ml | ALA4134808 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
19. | ALA4169575 | 4bq | Cmax | = | 162.4 | ng/ml | ALA4134807 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
20. | ALA4169575 | 4bq | Tmax | = | 0.25 | hr | ALA4134806 | hr | Mus musculus |