# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Ro 61-8048 | 16 | PPB | > | 99 | % | ALA3533679 | % | ||||
2. | Ro 61-8048 | 16 | PPB | > | 99 | % | ALA3533680 | % | ||||
3. | Ro 61-8048 | 16 | PPB | > | 99 | % | ALA3533681 | % | ||||
4. | Ro 61-8048 | 16 | Papp | = | 100 | nm/s | ALA3533676 | nm/s | ||||
5. | Ro 61-8048 | 16 | Papp | = | 130 | nm/s | ALA3533674 | nm/s | ||||
6. | Ro 61-8048 | 16 | IC50 | = | 170 | nM | ALA3536664 | 6.77 | nM | Homo sapiens | ||
7. | Ro 61-8048 | 16 | Papp | = | 170 | nm/s | ALA3533673 | nm/s | ||||
8. | Ro 61-8048 | 16 | t1/2 | > | 200 | min | ALA3533322 | hr | ||||
9. | Ro 61-8048 | 16 | Cmax | = | 230 | nM | ALA3534868 | nM | Mus musculus | |||
10. | Ro 61-8048 | 16 | Cmax | = | 280 | nM | ALA3536672 | nM | Mus musculus | |||
11. | Ro 61-8048 | 16 | Cmax | = | 280 | nM | ALA3536673 | nM | Mus musculus | |||
12. | Ro 61-8048 | 16 | Papp | = | 330 | nm/s | ALA3533677 | nm/s | ||||
13. | Ro 61-8048 | 16 | Cmax | = | 530 | nM | ALA3532762 | nM | Mus musculus | |||
14. | Ro 61-8048 | 16 | Cmax | = | 550 | nM | ALA3532413 | nM | Mus musculus | |||
15. | Ro 61-8048 | 16 | Cmax | = | 800 | nM | ALA3535626 | nM | Mus musculus | |||
16. | Ro 61-8048 | 16 | AUClast | = | 1700 | nM.hr | ALA3541902 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
17. | Ro 61-8048 | 16 | AUClast | = | 2000 | nM.hr | ALA3534866 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
18. | Ro 61-8048 | 16 | AUC | = | 2100 | nM.hr | ALA3541903 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
19. | Ro 61-8048 | 16 | AUC | = | 2300 | nM.hr | ALA3534867 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
20. | Ro 61-8048 | 16 | AUClast | = | 4300 | nM.hr | ALA3532409 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus |