| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4171084 | 31 | CL free | = | 1446 | ml/min.kg | ALA4199519 | mL.min-1.kg-1 | Mus musculus | |||
| 2. | ALA4171084 | 31 | Ratio IC50 | = | 12 | ALA4199517 | ||||||
| 3. | ALA4171084 | 31 | logD | = | 1.2 | ALA4199516 | ||||||
| 4. | ALA4171084 | 31 | CLH | = | 9.33 | uL/min | ALA4199515 | uL/min | Homo sapiens | |||
| 5. | ALA4171084 | 31 | IC50 | = | 0.31 | uM | ALA4199514 | 6.51 | nM | Homo sapiens | ||
| 6. | ALA4171084 | 31 | IC50 | = | 2.2 | uM | ALA4199511 | 5.66 | nM | Homo sapiens | ||
| 7. | ALA4171084 | 31 | IC50 | = | 0.31 | uM | ALA4199510 | 6.51 | nM | Homo sapiens | ||
| 8. | ALA4171084 | 31 | IC50 | = | 0.026 | uM | ALA4199509 | 7.58 | nM | Homo sapiens | ||
| 9. | ALA4171084 | 31 | Vdss | = | 0.44 | L/Kg | ALA4151132 | L.kg-1 | Canis lupus familiaris | |||
| 10. | ALA4171084 | 31 | AUC | = | 8.78 | uM.hr | ALA4151131 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Canis lupus familiaris | ||
| 11. | ALA4171084 | 31 | CL | = | 0.75 | ml/min.kg | ALA4151130 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 12. | ALA4171084 | 31 | F | = | 100 | % | ALA4151129 | % | Rattus norvegicus | |||
| 13. | ALA4171084 | 31 | AUC | = | 11 | uM.hr | ALA4151128 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 14. | ALA4171084 | 31 | Vdss | = | 2.54 | L/Kg | ALA4151127 | L.kg-1 | Rattus norvegicus | |||
| 15. | ALA4171084 | 31 | AUC | = | 1.84 | uM.hr | ALA4151126 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 16. | ALA4171084 | 31 | CL | = | 9.1 | ml/min.kg | ALA4151125 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 17. | ALA4171084 | 31 | CLH | = | 1.7 | uL/min | ALA4151124 | uL/min | Homo sapiens | |||
| 18. | ALA4171084 | 31 | Papp | = | 18.8 | 10'-6 cm/s | ALA4151123 | 10'-6 cm/s | ||||
| 19. | ALA4171084 | 31 | solubility | = | 98 | uM | ALA4151122 | nM | ||||
| 20. | ALA4171084 | 31 | Ratio IC50 | = | 85 | ALA4151121 |
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