| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4171228 | 9; CD161 | IC50 | = | 3.9 | uM | ALA4185408 | 5.41 | nM | Homo sapiens | ||
| 2. | ALA4171228 | 9; CD161 | CL | = | 0.88 | L/hr/kg | ALA4185416 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 3. | ALA4171228 | 9; CD161 | AUCt | = | 29547 | ng.hr/ml | ALA4185414 | ng.hr.mL-1 | Rattus norvegicus | |||
| 4. | ALA4171228 | 9; CD161 | Cmax | = | 7333 | ng/ml | ALA4185413 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 5. | ALA4171228 | 9; CD161 | t1/2 | = | 2.9 | hr | ALA4185412 | hr | Rattus norvegicus | |||
| 6. | ALA4171228 | 9; CD161 | IC50 | = | 53 | nM | ALA4185403 | 7.28 | nM | Homo sapiens | ||
| 7. | ALA4171228 | 9; CD161 | IC50 | = | 26 | nM | ALA4185404 | 7.58 | nM | Homo sapiens | ||
| 8. | ALA4171228 | 9; CD161 | Ki | = | 1.4 | nM | ALA4185405 | 8.85 | nM | Homo sapiens | ||
| 9. | ALA4171228 | 9; CD161 | Ki | = | 8.2 | nM | ALA4185410 | 8.09 | nM | Homo sapiens | ||
| 10. | ALA4171228 | 9; CD161 | Activity | 0 | ALA4185493 | Dose-dependent effect | Homo sapiens | |||||
| 11. | ALA4171228 | 9; CD161 | INH | 0 | ALA4185492 | Dose-dependent effect | % | |||||
| 12. | ALA4171228 | 9; CD161 | INH | 0 | ALA4185491 | Dose-dependent effect | % | |||||
| 13. | ALA4171228 | 9; CD161 | Activity | 0 | ALA4185409 | Non-Toxic | Mus musculus | |||||
| 14. | ALA4171228 | 9; CD161 | Activity | 0 | ALA4185490 | Non-Toxic | Mus musculus | |||||
| 15. | ALA4171228 | 9; CD161 | TGI | 0 | ALA4185489 | Active | Homo sapiens | |||||
| 16. | ALA4171228 | 9; CD161 | IC50 | = | 1713 | nM | ALA4185488 | 5.77 | nM | Homo sapiens | ||
| 17. | ALA4171228 | 9; CD161 | Activity | 0 | ALA4185487 | Non-Toxic | Mus musculus | |||||
| 18. | ALA4171228 | 9; CD161 | Activity | 0 | ALA4185486 | Non-Toxic | Mus musculus | |||||
| 19. | ALA4171228 | 9; CD161 | IC50 | > | 2000 | nM | ALA4185485 | nM | Homo sapiens | |||
| 20. | ALA4171228 | 9; CD161 | IC50 | > | 2000 | nM | ALA4185484 | nM | Homo sapiens |
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