Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA4172540	19; VU6010572, (S)-enantiomer	CL	=	76.3	ml/min.kg	ALA4350345		mL.min-1.kg-1
2.	ALA4172540	19; VU6010572, (S)-enantiomer	MED	=	10	mg kg-1	ALA4350338		mg kg-1	Mus musculus
3.	ALA4172540	19; VU6010572, (S)-enantiomer	Vdss	=	2.05	L/Kg	ALA4350337		L.kg-1
4.	ALA4172540	19; VU6010572, (S)-enantiomer	MRT	=	26.9	min	ALA4350336		hr
5.	ALA4172540	19; VU6010572, (S)-enantiomer	t1/2	=	23.4	min	ALA4350335		hr
6.	ALA4172540	19; VU6010572, (S)-enantiomer	Activity	=	-5.7	%	ALA4350330		%	Rattus norvegicus
7.	ALA4172540	19; VU6010572, (S)-enantiomer	IC50	=	1.28	uM	ALA4350328	5.89	nM	Rattus norvegicus
8.	ALA4172540	19; VU6010572, (S)-enantiomer	IC50	=	245	nM	ALA4350327	6.61	nM	Rattus norvegicus
9.	ALA4172540	19; VU6010572, (S)-enantiomer	pIC50	=	6.61		ALA4134035	6.61	nM	Rattus norvegicus
10.	ALA4172540	19; VU6010572, (S)-enantiomer	INH	>	50	%	ALA4134134		%	Homo sapiens
11.	ALA4172540	19; VU6010572, (S)-enantiomer	INH	>	50	%	ALA4134133		%	Homo sapiens
12.	ALA4172540	19; VU6010572, (S)-enantiomer	INH	>	50	%	ALA4134132		%
13.	ALA4172540	19; VU6010572, (S)-enantiomer	INH	>	50	%	ALA4134131		%	Homo sapiens
14.	ALA4172540	19; VU6010572, (S)-enantiomer	INH	>	50	%	ALA4134130		%
15.	ALA4172540	19; VU6010572, (S)-enantiomer	INH	>	50	%	ALA4134129		%	Homo sapiens
16.	ALA4172540	19; VU6010572, (S)-enantiomer	INH	>	50	%	ALA4134128		%
17.	ALA4172540	19; VU6010572, (S)-enantiomer	INH	>	50	%	ALA4134127		%	Homo sapiens
18.	ALA4172540	19; VU6010572, (S)-enantiomer	INH	>	50	%	ALA4134126		%	Homo sapiens
19.	ALA4172540	19; VU6010572, (S)-enantiomer	INH	>	50	%	ALA4134125		%	Homo sapiens
20.	ALA4172540	19; VU6010572, (S)-enantiomer	INH	>	50	%	ALA4134124		%	Homo sapiens