| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4174690 | 1 | solubility | = | 482 | ug ml-1 | ALA4158599 | ug.mL-1 | ||||
| 2. | ALA4174690 | 1 | Time | = | 8 | hr | ALA4158621 | hr | ||||
| 3. | ALA4174690 | 1 | t1/2 | = | 1.25 | hr | ALA4158620 | hr | ||||
| 4. | ALA4174690 | 1 | Activity | 0 | ALA4158619 | Dose-dependent effect | Respiratory syncytial virus | |||||
| 5. | ALA4174690 | 1 | Activity | = | 1 | deltalog10pfu/g | ALA4158618 | deltalog10pfu/g | Respiratory syncytial virus | |||
| 6. | ALA4174690 | 1 | IC50 | = | 2.56 | uM | ALA4158617 | 5.59 | nM | Human respiratory syncytial virus | ||
| 7. | ALA4174690 | 1 | Ratio AUC | = | 78 | ALA4158616 | ||||||
| 8. | ALA4174690 | 1 | AUC | = | 769641 | ug/L.hr | ALA4158615 | ng.hr.mL-1 | ||||
| 9. | ALA4174690 | 1 | F | = | 132 | % | ALA4158614 | % | Mus musculus | |||
| 10. | ALA4174690 | 1 | F | = | 66 | % | ALA4158613 | % | Mus musculus | |||
| 11. | ALA4174690 | 1 | F | = | 36 | % | ALA4158612 | % | Mus musculus | |||
| 12. | ALA4174690 | 1 | AUC | = | 44532 | ug/L.hr | ALA4158611 | ng.hr.mL-1 | ||||
| 13. | ALA4174690 | 1 | AUC | = | 9884 | ug/L.hr | ALA4158610 | ng.hr.mL-1 | ||||
| 14. | ALA4174690 | 1 | AUC | = | 1352 | ug/L.hr | ALA4158609 | ng.hr.mL-1 | ||||
| 15. | ALA4174690 | 1 | AUC | = | 150 | ug/L.hr | ALA4158608 | ng.hr.mL-1 | Mus musculus | |||
| 16. | ALA4174690 | 1 | CL | = | 222 | ml/min.kg | ALA4158607 | mL.min-1.kg-1 | Mus musculus | |||
| 17. | ALA4174690 | 1 | Vdss | = | 4.7 | L/Kg | ALA4158606 | L.kg-1 | Mus musculus | |||
| 18. | ALA4174690 | 1 | t1/2 | = | 2.9 | hr | ALA4158605 | hr | Mus musculus | |||
| 19. | ALA4174690 | 1 | t1/2 | = | 2.3 | hr | ALA4158604 | hr | Mus musculus | |||
| 20. | ALA4174690 | 1 | t1/2 | = | 1.3 | hr | ALA4158603 | hr | Mus musculus |
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