# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4174695 | 12 | pIC50 | = | 6.1 | ALA4145001 | 6.10 | nM | Homo sapiens | |||
2. | ALA4174695 | 12 | INH | 0 | ALA4145001 | Dose-dependent effect | % | Homo sapiens | ||||
3. | ALA4174695 | 12 | IC50 | > | 30 | uM | ALA4145003 | nM | Rattus norvegicus | |||
4. | ALA4174695 | 12 | IC50 | = | 62 | nM | ALA4145002 | 7.21 | nM | Homo sapiens | ||
5. | ALA4174695 | 12 | IC50 | = | 777 | nM | ALA4145001 | 6.11 | nM | Homo sapiens | ||
6. | ALA4174695 | 12 | Papp | = | 19 | 10'-6 cm/s | ALA4144999 | 10'-6 cm/s | ||||
7. | ALA4174695 | 12 | CLH(app) | = | 35 | ml/min.kg | ALA4144998 | mL.min-1.kg-1 | ||||
8. | ALA4174695 | 12 | logD | = | 3 | ALA4144997 | ||||||
9. | ALA4174695 | 12 | Ki | > | 40 | uM | ALA4144996 | nM | Homo sapiens | |||
10. | ALA4174695 | 12 | pIC50 | = | 7 | ALA4144993 | 7.00 | nM | Homo sapiens | |||
11. | ALA4174695 | 12 | IC50 | = | 0.085 | uM | ALA4144993 | 7.07 | nM | Homo sapiens |