# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4176386 | 3 | F | = | 100 | % | ALA4157541 | % | Rattus norvegicus | |||
2. | ALA4176386 | 3 | beta t1/2 | = | 24 | hr | ALA4157540 | hr | Rattus norvegicus | |||
3. | ALA4176386 | 3 | Vdss | = | 12 | L/Kg | ALA4157539 | L.kg-1 | Rattus norvegicus | |||
4. | ALA4176386 | 3 | CL | = | 0.42 | L/hr/kg | ALA4157538 | mL.min-1.kg-1 | Rattus norvegicus | |||
5. | ALA4176386 | 3 | F | = | 55 | % | ALA4157534 | % | Canis lupus familiaris | |||
6. | ALA4176386 | 3 | beta t1/2 | = | 25 | hr | ALA4157532 | hr | Canis lupus familiaris | |||
7. | ALA4176386 | 3 | Vdss | = | 2.3 | L/Kg | ALA4157530 | L.kg-1 | Canis lupus familiaris | |||
8. | ALA4176386 | 3 | CL | = | 0.08 | L/hr/kg | ALA4157528 | mL.min-1.kg-1 | Canis lupus familiaris | |||
9. | ALA4176386 | 3 | Activity | = | 45 | % | ALA4157524 | % | Homo sapiens | |||
10. | ALA4176386 | 3 | Activity | = | 10 | % | ALA4157523 | % | Homo sapiens | |||
11. | ALA4176386 | 3 | logD | = | 2.2 | ALA4157522 | ||||||
12. | ALA4176386 | 3 | permeability | = | 13 | 10'-6 cm/s | ALA4157521 | 10'-6 cm/s | ||||
13. | ALA4176386 | 3 | permeability | = | 1.5 | 10'-6 cm/s | ALA4157520 | 10'-6 cm/s | ||||
14. | ALA4176386 | 3 | Fu | = | 41 | % | ALA4157516 | |||||
15. | ALA4176386 | 3 | Fu | = | 100 | % | ALA4157515 | |||||
16. | ALA4176386 | 3 | CC50 | > | 40000 | nM | ALA4157514 | nM | Homo sapiens | |||
17. | ALA4176386 | 3 | EC50 | = | 98 | nM | ALA4157513 | 7.01 | nM | Hepacivirus hominis | ||
18. | ALA4176386 | 3 | Kd | = | 5 | nM | ALA4157512 | 8.30 | nM | Homo sapiens | ||
19. | ALA4176386 | 3 | t1/2 | > | 1500 | min | ALA4157518 | hr | ||||
20. | ALA4176386 | 3 | t1/2 | > | 1500 | min | ALA4157517 | hr |