| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  TUG-1375 | 31; TUG-1375 | FC | = | 50 | ALA4158202 | Mus musculus | |||||
| 2. | TUG-1375 | 31; TUG-1375 | pEC50 | = | 5.3 | ALA4158201 | 5.30 | nM | Mus musculus | |||
| 3. | TUG-1375 | 31; TUG-1375 | Activity | 0 | ALA4158200 | Active | Homo sapiens | |||||
| 4. | TUG-1375 | 31; TUG-1375 | Activity | 0 | ALA4158199 | Active | Homo sapiens | |||||
| 5. | TUG-1375 | 31; TUG-1375 | Activity | 0 | ALA4158198 | Active | Homo sapiens | |||||
| 6. | TUG-1375 | 31; TUG-1375 | t1/2 | = | 82 | min | ALA4158197 | hr | Mus musculus | |||
| 7. | TUG-1375 | 31; TUG-1375 | AUC | = | 60500 | ng.min/ml | ALA4158196 | ng.hr.mL-1 | Mus musculus | |||
| 8. | TUG-1375 | 31; TUG-1375 | CLH | < | 8 | uL/min | ALA4158195 | uL/min | ||||
| 9. | TUG-1375 | 31; TUG-1375 | pEC50 | = | 6.44 | ALA4158194 | 6.44 | nM | Mus musculus | |||
| 10. | TUG-1375 | 31; TUG-1375 | F | = | 32 | % | ALA4158193 | % | Mus musculus | |||
| 11. | TUG-1375 | 31; TUG-1375 | AUC | = | 156000 | ng.min/ml | ALA4158192 | ng.hr.mL-1 | Mus musculus | |||
| 12. | TUG-1375 | 31; TUG-1375 | Cmax | = | 2880 | ng/ml | ALA4158191 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 13. | TUG-1375 | 31; TUG-1375 | Tmax | = | 15 | min | ALA4158190 | hr | Mus musculus | |||
| 14. | TUG-1375 | 31; TUG-1375 | CL | = | 20.3 | ml/min.kg | ALA4158189 | mL.min-1.kg-1 | Mus musculus | |||
| 15. | TUG-1375 | 31; TUG-1375 | Vd | = | 4050 | ml/kg | ALA4158188 | L.kg-1 | Mus musculus | |||
| 16. | TUG-1375 | 31; TUG-1375 | AUC | = | 246000 | ng.min/ml | ALA4158187 | ng.hr.mL-1 | Mus musculus | |||
| 17. | TUG-1375 | 31; TUG-1375 | t1/2 | = | 138 | min | ALA4158186 | hr | Mus musculus | |||
| 18. | TUG-1375 | 31; TUG-1375 | Drug recovery | = | 72 | % | ALA4158185 | % | Mus musculus | |||
| 19. | TUG-1375 | 31; TUG-1375 | Stability | = | 82 | % | ALA4158184 | % | ||||
| 20. | TUG-1375 | 31; TUG-1375 | Stability | = | 100 | % | ALA4158183 | % |
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