# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4176594 | 7r | solubility | > | 480 | ug ml-1 | ALA4158599 | ug.mL-1 | ||||
2. | ALA4176594 | 7r | t1/2 | = | 4.1 | hr | ALA4158602 | hr | Rattus norvegicus | |||
3. | ALA4176594 | 7r | Fu | = | 10 | % | ALA4158601 | |||||
4. | ALA4176594 | 7r | Fu | = | 3 | % | ALA4158600 | |||||
5. | ALA4176594 | 7r | CLH | = | 23 | ml/min.kg | ALA4158594 | mL.min-1.kg-1 | ||||
6. | ALA4176594 | 7r | CLH | = | 12 | ml/min.kg | ALA4158593 | mL.min-1.kg-1 | ||||
7. | ALA4176594 | 7r | F | = | 29 | % | ALA4158592 | % | Rattus norvegicus | |||
8. | ALA4176594 | 7r | Vdss | = | 20 | L/Kg | ALA4158591 | L.kg-1 | Rattus norvegicus | |||
9. | ALA4176594 | 7r | CL | = | 53 | ml/min.kg | ALA4158590 | mL.min-1.kg-1 | Rattus norvegicus | |||
10. | ALA4176594 | 7r | AUC | = | 1267 | hr.ng/ml | ALA4158589 | ng.hr.mL-1 | Rattus norvegicus | |||
11. | ALA4176594 | 7r | AUC | = | 466 | hr.ng/ml | ALA4158588 | ng.hr.mL-1 | Rattus norvegicus | |||
12. | ALA4176594 | 7r | CLH | = | 37 | ml/min.kg | ALA4158587 | mL.min-1.kg-1 | ||||
13. | ALA4176594 | 7r | Peff | = | 0.59 | ucm/s | ALA4158586 | ucm/s | ||||
14. | ALA4176594 | 7r | Ratio CC50/EC50 | = | 17200 | ALA4158585 | ||||||
15. | ALA4176594 | 7r | CC50 | = | 86 | uM | ALA4158584 | nM | Homo sapiens | |||
16. | ALA4176594 | 7r | EC50 | = | 0.005 | uM | ALA4158583 | 8.30 | nM | Human respiratory syncytial virus |