# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4203469 | 26a | t1/2 | = | 0.94 | hr | ALA4179245 | hr | Rattus norvegicus | |||
2. | ALA4203469 | 26a | CL | = | 33.3 | ml/min.kg | ALA4179243 | mL.min-1.kg-1 | Rattus norvegicus | |||
3. | ALA4203469 | 26a | Vdss | = | 2 | L/Kg | ALA4179241 | L.kg-1 | Rattus norvegicus | |||
4. | ALA4203469 | 26a | AUCt | = | 1.42 | uM.hr | ALA4179239 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
5. | ALA4203469 | 26a | Drug recovery | = | 94 | % | ALA4179238 | % | ||||
6. | ALA4203469 | 26a | Drug recovery | = | 92 | % | ALA4179237 | % | ||||
7. | ALA4203469 | 26a | Drug recovery | = | 93 | % | ALA4179236 | % | ||||
8. | ALA4203469 | 26a | Drug recovery | = | 79 | % | ALA4179235 | % | ||||
9. | ALA4203469 | 26a | Drug recovery | = | 87 | % | ALA4179234 | % | ||||
10. | ALA4203469 | 26a | Drug recovery | = | 89 | % | ALA4179233 | % | ||||
11. | ALA4203469 | 26a | t1/2 | > | 30 | min | ALA4179232 | hr | ||||
12. | ALA4203469 | 26a | t1/2 | > | 30 | min | ALA4179231 | hr | ||||
13. | ALA4203469 | 26a | t1/2 | > | 30 | min | ALA4179228 | hr | ||||
14. | ALA4203469 | 26a | Drug metabolism | = | 0.06 | nmol/min/mg | ALA4179230 | nmol/min/mg | ||||
15. | ALA4203469 | 26a | Drug metabolism | = | 0.04 | nmol/min/mg | ALA4179229 | nmol/min/mg | ||||
16. | ALA4203469 | 26a | Drug metabolism | = | 0.04 | nmol/min/mg | ALA4179227 | nmol/min/mg | ||||
17. | ALA4203469 | 26a | Ki | = | 5.9 | nM | ALA4179226 | 8.23 | nM | Bos taurus |