# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4204025 | (3S,5S)-3r | F | = | 73 | % | ALA4188435 | % | Rattus norvegicus | |||
2. | ALA4204025 | (3S,5S)-3r | AUC | = | 759 | ng.hr/ml | ALA4188434 | ng.hr.mL-1 | Rattus norvegicus | |||
3. | ALA4204025 | (3S,5S)-3r | Vdss | = | 2.25 | L/Kg | ALA4188433 | L.kg-1 | Rattus norvegicus | |||
4. | ALA4204025 | (3S,5S)-3r | CL | = | 22 | mg/ml/kg | ALA4188432 | mg/ml/kg | Rattus norvegicus | |||
5. | ALA4204025 | (3S,5S)-3r | t1/2 | = | 1.32 | hr | ALA4188431 | hr | Rattus norvegicus | |||
6. | ALA4204025 | (3S,5S)-3r | CC50 | > | 3 | uM | ALA4188430 | nM | Homo sapiens | |||
7. | ALA4204025 | (3S,5S)-3r | EC50 | = | 0.009 | uM | ALA4188428 | 8.05 | nM | Hepatitis C virus | ||
8. | ALA4204025 | (3S,5S)-3r | EC50 | = | 0.003 | uM | ALA4188420 | 8.52 | nM | Hepatitis C virus | ||
9. | ALA4204025 | (3S,5S)-3r | EC50 | = | 0.006 | uM | ALA4188427 | 8.22 | nM | Hepatitis C virus | ||
10. | ALA4204025 | (3S,5S)-3r | EC50 | = | 0.012 | uM | ALA4188426 | 7.92 | nM | Hepatitis C virus | ||
11. | ALA4204025 | (3S,5S)-3r | Stability | = | 100 | % | ALA4188425 | % | ||||
12. | ALA4204025 | (3S,5S)-3r | Stability | = | 60 | % | ALA4188424 | % | ||||
13. | ALA4204025 | (3S,5S)-3r | EC50 | = | 0.009 | uM | ALA4188422 | 8.05 | nM | Hepatitis C virus |