# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4204700 | 10n | Activity | 0 | ALA4198067 | Not Active | Homo sapiens | |||||
2. | ALA4204700 | 10n | Activity | 0 | ALA4198066 | Not Active | Homo sapiens | |||||
3. | ALA4204700 | 10n | Activity | 0 | ALA4198065 | Not Active | Homo sapiens | |||||
4. | ALA4204700 | 10n | Activity | 0 | ALA4198064 | Dose-dependent effect | Homo sapiens | |||||
5. | ALA4204700 | 10n | CLH | = | 7.4 | ml/min.kg | ALA4198063 | mL.min-1.kg-1 | ||||
6. | ALA4204700 | 10n | t1/2 | = | 2.8 | hr | ALA4198062 | hr | ||||
7. | ALA4204700 | 10n | CLH | = | 37 | ml/min.kg | ALA4198061 | mL.min-1.kg-1 | ||||
8. | ALA4204700 | 10n | t1/2 | = | 1.26 | hr | ALA4198060 | hr | ||||
9. | ALA4204700 | 10n | CLH | = | 65.1 | ml/min.kg | ALA4198059 | mL.min-1.kg-1 | ||||
10. | ALA4204700 | 10n | t1/2 | = | 0.88 | hr | ALA4198058 | hr | ||||
11. | ALA4204700 | 10n | Ratio IC50 | = | 0.32 | ALA4198057 | ||||||
12. | ALA4204700 | 10n | Ratio IC50 | = | 0.34 | ALA4198056 | ||||||
13. | ALA4204700 | 10n | IC50 | = | 0.1 | uM | ALA4198055 | 7.00 | nM | Homo sapiens | ||
14. | ALA4204700 | 10n | IC50 | = | 0.31 | uM | ALA4198054 | 6.51 | nM | Homo sapiens | ||
15. | ALA4204700 | 10n | IC50 | = | 0.44 | uM | ALA4198053 | 6.36 | nM | |||
16. | ALA4204700 | 10n | IC50 | = | 1.28 | uM | ALA4198052 | 5.89 | nM | Homo sapiens | ||
17. | ALA4204700 | 10n | Ratio IC50 | = | 3.1 | ALA4198051 | ||||||
18. | ALA4204700 | 10n | IC50 | = | 2.8 | uM | ALA4198050 | 5.55 | nM | |||
19. | ALA4204700 | 10n | IC50 | = | 0.9 | uM | ALA4198049 | 6.05 | nM | Homo sapiens | ||
20. | ALA4204700 | 10n | IC50 | = | 6.2 | uM | ALA4198048 | 5.21 | nM | Homo sapiens |