# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4205613 | 10f | Activity | 0 | ALA4198074 | Non-Toxic | Mus musculus | |||||
2. | ALA4205613 | 10f | Activity | 0 | ALA4198072 | Non-Toxic | Mus musculus | |||||
3. | ALA4205613 | 10f | Activity | = | 0.85 | g | ALA4198070 | g | Homo sapiens | |||
4. | ALA4205613 | 10f | TGI | = | 68.6 | % | ALA4198068 | % | Homo sapiens | |||
5. | ALA4205613 | 10f | Activity | 0 | ALA4198067 | Not Active | Homo sapiens | |||||
6. | ALA4205613 | 10f | Activity | 0 | ALA4198066 | Not Active | Homo sapiens | |||||
7. | ALA4205613 | 10f | Activity | 0 | ALA4198065 | Not Active | Homo sapiens | |||||
8. | ALA4205613 | 10f | Activity | 0 | ALA4198064 | Dose-dependent effect | Homo sapiens | |||||
9. | ALA4205613 | 10f | CLH | = | 4.5 | ml/min.kg | ALA4198063 | mL.min-1.kg-1 | ||||
10. | ALA4205613 | 10f | t1/2 | = | 4.59 | hr | ALA4198062 | hr | ||||
11. | ALA4205613 | 10f | CLH | = | 36.1 | ml/min.kg | ALA4198061 | mL.min-1.kg-1 | ||||
12. | ALA4205613 | 10f | t1/2 | = | 1.29 | hr | ALA4198060 | hr | ||||
13. | ALA4205613 | 10f | CLH | = | 42.1 | ml/min.kg | ALA4198059 | mL.min-1.kg-1 | ||||
14. | ALA4205613 | 10f | t1/2 | = | 1.36 | hr | ALA4198058 | hr | ||||
15. | ALA4205613 | 10f | Ratio IC50 | = | 0.17 | ALA4198057 | ||||||
16. | ALA4205613 | 10f | Ratio IC50 | = | 0.13 | ALA4198056 | ||||||
17. | ALA4205613 | 10f | IC50 | = | 0.027 | uM | ALA4198055 | 7.57 | nM | Homo sapiens | ||
18. | ALA4205613 | 10f | IC50 | = | 0.16 | uM | ALA4198054 | 6.80 | nM | Homo sapiens | ||
19. | ALA4205613 | 10f | IC50 | = | 0.17 | uM | ALA4198053 | 6.77 | nM | |||
20. | ALA4205613 | 10f | IC50 | = | 1.36 | uM | ALA4198052 | 5.87 | nM | Homo sapiens |