Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4205936	4o	Activity		0		ALA4189947		Active		Rattus norvegicus
2.	ALA4205936	4o	Imax	=	100	%	ALA4189946			%	Homo sapiens
3.	ALA4205936	4o	IC50	=	1.9	uM	ALA4189945	5.72		nM	Homo sapiens
4.	ALA4205936	4o	EC50	=	6	nM	ALA4189944	8.22		nM	Rattus norvegicus
5.	ALA4205936	4o	EC50	=	6	nM	ALA4189943	8.22		nM	Homo sapiens
6.	ALA4205936	4o	Activity		0		ALA4189942		Active		Mus musculus
7.	ALA4205936	4o	Activity		0		ALA4189939		Dose-dependent effect		Rattus norvegicus
8.	ALA4205936	4o	IC50	>	10	uM	ALA4189938			nM	Homo sapiens
9.	ALA4205936	4o	IC50	>	10	uM	ALA4189937			nM	Homo sapiens
10.	ALA4205936	4o	Fu	=	24	%	ALA4189936
11.	ALA4205936	4o	Fu	=	17	%	ALA4189935
12.	ALA4205936	4o	ED50	=	6.15	mg kg-1	ALA4189933			mg.kg-1	Rattus norvegicus
13.	ALA4205936	4o	Activity		0		ALA4189932		Not Active		Rattus norvegicus
14.	ALA4205936	4o	Activity		0		ALA4189929		Active		Rattus norvegicus
15.	ALA4205936	4o	BPR	=	0.8		ALA4189927
16.	ALA4205936	4o	CL	=	35	ml/min.kg	ALA4189926			mL.min-1.kg-1	Rattus norvegicus
17.	ALA4205936	4o	AUC	=	1753	ng.hr/ml	ALA4189925			ng.hr.mL-1	Rattus norvegicus
18.	ALA4205936	4o	Cmax	=	948	ng/ml	ALA4189924		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Rattus norvegicus
19.	ALA4205936	4o	F	=	124	%	ALA4189923			%	Rattus norvegicus
20.	ALA4205936	4o	Drug metabolism	=	29.9	%	ALA4189922			%