| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4206744 | IIQ | INH | 0 | ALA4201460 | Active | % | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | ||||
| 2. | ALA4206744 | IIQ | EC50 | = | 1.87 | uM | ALA4201485 | 5.73 | nM | Influenza B virus | ||
| 3. | ALA4206744 | IIQ | EC50 | = | 1.02 | uM | ALA4201484 | 5.99 | nM | Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus) | ||
| 4. | ALA4206744 | IIQ | CC50 | > | 100 | uM | ALA4201483 | nM | Homo sapiens | |||
| 5. | ALA4206744 | IIQ | EC50 | = | 3.63 | uM | ALA4201482 | 5.44 | nM | Human immunodeficiency virus 1 | ||
| 6. | ALA4206744 | IIQ | Vdss | = | 197.8 | ml/kg | ALA4201481 | L.kg-1 | Rattus norvegicus | |||
| 7. | ALA4206744 | IIQ | Cmax | = | 97.6 | ug ml-1 | ALA4201480 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 8. | ALA4206744 | IIQ | CL | = | 20.7 | ml/hr/kg | ALA4201479 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 9. | ALA4206744 | IIQ | t1/2 | = | 6.6 | hr | ALA4201478 | hr | Rattus norvegicus | |||
| 10. | ALA4206744 | IIQ | MRT(t) | = | 4.1 | hr | ALA4201477 | hr | Rattus norvegicus | |||
| 11. | ALA4206744 | IIQ | AUCt | = | 234.7 | ug/ml.hr | ALA4201476 | ng.hr.mL-1 | Rattus norvegicus | |||
| 12. | ALA4206744 | IIQ | solubility | = | 8.87 | mg/ml | ALA4201475 | ug.mL-1 | ||||
| 13. | ALA4206744 | IIQ | Activity | 0 | ALA4201470 | Active | Middle East respiratory syndrome-related coronavirus | |||||
| 14. | ALA4206744 | IIQ | K | = | 1.04 | 10'5/M | ALA4201468 | 10'5/M | ||||
| 15. | ALA4206744 | IIQ | Activity | 0 | ALA4201467 | Active | ||||||
| 16. | ALA4206744 | IIQ | Activity | 0 | ALA4201466 | Active | ||||||
| 17. | ALA4206744 | IIQ | Tm | = | 83.1 | degrees C | ALA4201465 | degrees C | ||||
| 18. | ALA4206744 | IIQ | Tm | > | 90 | degrees C | ALA4201464 | degrees C | ||||
| 19. | ALA4206744 | IIQ | EC50 | = | 0.11 | uM | ALA4201438 | 6.96 | nM | |||
| 20. | ALA4206744 | IIQ | CC50 | > | 100 | uM | ALA4201439 | nM | Homo sapiens |
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