| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4207565 | 2e | INH | 0 | ALA4197840 | Not Active | % | Homo sapiens | ||||
| 2. | ALA4207565 | 2e | INH | 0 | ALA4197839 | Not Active | % | Homo sapiens | ||||
| 3. | ALA4207565 | 2e | INH | 0 | ALA4197838 | Active | % | Homo sapiens | ||||
| 4. | ALA4207565 | 2e | INH | = | 85 | % | ALA4197837 | % | Ebolavirus | |||
| 5. | ALA4207565 | 2e | INH | = | 23 | % | ALA4197836 | % | Ebolavirus | |||
| 6. | ALA4207565 | 2e | INH | < | 38 | % | ALA4197835 | % | Ebolavirus | |||
| 7. | ALA4207565 | 2e | Activity | = | 45 | % | ALA4197834 | % | Marburgvirus | |||
| 8. | ALA4207565 | 2e | Activity | = | 58 | % | ALA4197833 | % | Ebolavirus | |||
| 9. | ALA4207565 | 2e | LD50 | = | 28.3 | mg kg-1 | ALA4197832 | mg.kg-1 | Mus musculus | |||
| 10. | ALA4207565 | 2e | LD50 | > | 100 | mg kg-1 | ALA4197831 | mg.kg-1 | Mus musculus | |||
| 11. | ALA4207565 | 2e | LD50 | = | 458 | mg kg-1 | ALA4197830 | mg.kg-1 | Mus musculus | |||
| 12. | ALA4207565 | 2e | t1/2 | = | 4.14 | hr | ALA4197829 | hr | Mus musculus | |||
| 13. | ALA4207565 | 2e | MRT | = | 4.89 | hr | ALA4197828 | hr | Mus musculus | |||
| 14. | ALA4207565 | 2e | AUC | = | 4.89 | uM.hr | ALA4197827 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 15. | ALA4207565 | 2e | AUCt | = | 2.74 | uM.hr | ALA4197826 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 16. | ALA4207565 | 2e | Cmax | = | 0.29 | uM | ALA4197825 | nM | Mus musculus | |||
| 17. | ALA4207565 | 2e | Tmax | = | 0.67 | hr | ALA4197824 | hr | Mus musculus | |||
| 18. | ALA4207565 | 2e | Ratio CC50/EC50 | > | 28.2 | ALA4197823 | ||||||
| 19. | ALA4207565 | 2e | Ratio CC50/EC50 | > | 41.7 | ALA4197822 | ||||||
| 20. | ALA4207565 | 2e | CC50 | > | 200 | uM | ALA4197821 | nM | Homo sapiens |
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