| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4208172 | 10d | Cmax | = | 343 | ng/ml | ALA4188525 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 2. | ALA4208172 | 10d | IC50 | = | 6.38 | uM | ALA4188524 | 5.20 | nM | Homo sapiens | ||
| 3. | ALA4208172 | 10d | IC50 | = | 232 | nM | ALA4188523 | 6.63 | nM | Homo sapiens | ||
| 4. | ALA4208172 | 10d | IC50 | = | 0.9 | nM | ALA4188522 | 9.05 | nM | Homo sapiens | ||
| 5. | ALA4208172 | 10d | MRT | = | 7.58 | hr | ALA4188528 | hr | Rattus norvegicus | |||
| 6. | ALA4208172 | 10d | t1/2 | = | 4.62 | hr | ALA4188527 | hr | Rattus norvegicus | |||
| 7. | ALA4208172 | 10d | AUC | = | 3746 | ng/mL.hr | ALA4188526 | ng.hr.mL-1 | Rattus norvegicus | |||
| 8. | ALA4208172 | 10d | IC50 | = | 2670 | nM | ALA4188520 | 5.57 | nM | Homo sapiens | ||
| 9. | ALA4208172 | 10d | IC50 | = | 7.4 | nM | ALA4188521 | 8.13 | nM | Homo sapiens | ||
| 10. | ALA4208172 | 10d | Vz/F | = | 8751 | ml/kg | ALA4188530 | L.kg-1 | Rattus norvegicus | |||
| 11. | ALA4208172 | 10d | CL/F | = | 21.9 | ml/min.kg | ALA4188529 | mL.min-1.kg-1 | Rattus norvegicus |
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