# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4213410 | 8a | IC50 | = | 18 | nM | ALA4186869 | 7.75 | nM | Homo sapiens | ||
2. | ALA4213410 | 8a | IC50 | = | 13 | nM | ALA4186870 | 7.89 | nM | Homo sapiens | ||
3. | ALA4213410 | 8a | AUC | = | 0.37 | microg.hr/mL | ALA4186868 | ng.hr.mL-1 | Mus musculus | |||
4. | ALA4213410 | 8a | Ratio IC50 | > | 192 | ALA4186867 | ||||||
5. | ALA4213410 | 8a | Ratio IC50 | > | 192 | ALA4186866 | ||||||
6. | ALA4213410 | 8a | INH | = | 71 | % | ALA4186871 | % | Mus musculus | |||
7. | ALA4213410 | 8a | Cmax | = | 9.12 | ug ml-1 | ALA4186872 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA4213410 | 8a | Tmax | = | 1 | hr | ALA4186873 | hr | ||||
9. | ALA4213410 | 8a | AUC | = | 47.4 | microg.hr/mL | ALA4186874 | ng.hr.mL-1 | ||||
10. | ALA4213410 | 8a | Drug uptake | 0 | ALA4186875 | Active | ||||||
11. | ALA4213410 | 8a | Drug uptake | 0 | ALA4186876 | Tde | ||||||
12. | ALA4213410 | 8a | Drug uptake | 0 | ALA4186877 | Active | ||||||
13. | ALA4213410 | 8a | Ratio IC50 | > | 250 | ALA4186878 | ||||||
14. | ALA4213410 | 8a | Ratio IC50 | > | 250 | ALA4186879 | ||||||
15. | ALA4213410 | 8a | Ratio IC50 | > | 250 | ALA4186880 | ||||||
16. | ALA4213410 | 8a | Ratio IC50 | > | 250 | ALA4186881 | ||||||
17. | ALA4213410 | 8a | Ratio IC50 | > | 250 | ALA4186882 | ||||||
18. | ALA4213410 | 8a | Ratio IC50 | > | 250 | ALA4186883 | ||||||
19. | ALA4213410 | 8a | Ratio IC50 | > | 250 | ALA4186884 | ||||||
20. | ALA4213410 | 8a | Ratio IC50 | > | 250 | ALA4186885 |