# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4214079 | 13l | IC50 | = | 3 | nM | ALA4328867 | 8.52 | nM | Peptoclostridium difficile | ||
2. | ALA4214079 | 13l | Stability | 0 | ALA4328866 | Unstable | % | |||||
3. | ALA4214079 | 13l | Stability | 0 | ALA4187445 | Unstable | % | |||||
4. | ALA4214079 | 13l | Stability | = | 50 | % | ALA4187444 | % | ||||
5. | ALA4214079 | 13l | Tmax | = | 0.5 | hr | ALA4187443 | hr | Mus musculus | |||
6. | ALA4214079 | 13l | Cmax | = | 27 | ng/ml | ALA4187442 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
7. | ALA4214079 | 13l | Cmax | = | 2 | ng/ml | ALA4187441 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
8. | ALA4214079 | 13l | AUC | = | 181 | ng/mL.hr | ALA4187440 | ng.hr.mL-1 | Mus musculus | |||
9. | ALA4214079 | 13l | AUC | = | 2 | ng/mL.hr | ALA4187439 | ng.hr.mL-1 | Mus musculus | |||
10. | ALA4214079 | 13l | Vz | 0 | ALA4187438 | Not Determined | Mus musculus | |||||
11. | ALA4214079 | 13l | beta t1/2 | 0 | ALA4187437 | Not Determined | Mus musculus | |||||
12. | ALA4214079 | 13l | CL | 0 | ALA4187436 | Not Determined | Mus musculus | |||||
13. | ALA4214079 | 13l | Activity | 0 | ALA4187435 | Non-Toxic | Bacteroides fragilis | |||||
14. | ALA4214079 | 13l | Activity | 0 | ALA4187434 | Non-Toxic | Bifidobacterium longum | |||||
15. | ALA4214079 | 13l | Activity | 0 | ALA4187433 | Non-Toxic | Limosilactobacillus reuteri | |||||
16. | ALA4214079 | 13l | Activity | 0 | ALA4187432 | Not Active | Clostridioides difficile | |||||
17. | ALA4214079 | 13l | Stability | = | 77 | % | ALA4187431 | % | ||||
18. | ALA4214079 | 13l | Stability | = | 90 | % | ALA4187430 | % | ||||
19. | ALA4214079 | 13l | IC50 | = | 2.6 | uM | ALA4187429 | 5.58 | nM | Peptoclostridium difficile | ||
20. | ALA4214079 | 13l | IC50 | = | 0.007 | uM | ALA4187427 | 8.15 | nM | Peptoclostridium difficile |