Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4214511	7b	t1/2	=	2.21	hr	ALA4179246			hr	Rattus norvegicus
2.	ALA4214511	7b	CL	=	59	ml/min.kg	ALA4179244			mL.min-1.kg-1	Rattus norvegicus
3.	ALA4214511	7b	Vdss	=	7.01	L/Kg	ALA4179242			L.kg-1	Rattus norvegicus
4.	ALA4214511	7b	AUCt	=	2.21	uM.hr	ALA4179240		standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW	ng.hr.mL-1	Rattus norvegicus
5.	ALA4214511	7b	Drug recovery	=	95	%	ALA4179238			%
6.	ALA4214511	7b	Drug recovery	=	93	%	ALA4179237			%
7.	ALA4214511	7b	Drug recovery	=	94	%	ALA4179236			%
8.	ALA4214511	7b	Drug recovery	=	99	%	ALA4179235			%
9.	ALA4214511	7b	Drug recovery	=	93	%	ALA4179234			%
10.	ALA4214511	7b	Drug recovery	=	85	%	ALA4179233			%
11.	ALA4214511	7b	t1/2	>	30	min	ALA4179232			hr
12.	ALA4214511	7b	t1/2	>	30	min	ALA4179231			hr
13.	ALA4214511	7b	t1/2	>	30	min	ALA4179228			hr
14.	ALA4214511	7b	Drug metabolism	<	0.04	nmol/min/mg	ALA4179230			nmol/min/mg
15.	ALA4214511	7b	Drug metabolism	<	0.04	nmol/min/mg	ALA4179229			nmol/min/mg
16.	ALA4214511	7b	Drug metabolism	=	0.04	nmol/min/mg	ALA4179227			nmol/min/mg
17.	ALA4214511	7b	Ki	=	5.2	nM	ALA4179226	8.28		nM	Bos taurus