# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4215036 | 13j | IC50 | = | 1 | nM | ALA4328867 | 9.00 | nM | Peptoclostridium difficile | ||
2. | ALA4215036 | 13j | Stability | 0 | ALA4187446 | Unstable | % | |||||
3. | ALA4215036 | 13j | Tmax | = | 0.25 | hr | ALA4187443 | hr | Mus musculus | |||
4. | ALA4215036 | 13j | Cmax | = | 2687 | ng/ml | ALA4187442 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
5. | ALA4215036 | 13j | Cmax | = | 1034 | ng/ml | ALA4187441 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
6. | ALA4215036 | 13j | AUC | = | 1068 | ng/mL.hr | ALA4187440 | ng.hr.mL-1 | Mus musculus | |||
7. | ALA4215036 | 13j | AUC | = | 200 | ng/mL.hr | ALA4187439 | ng.hr.mL-1 | Mus musculus | |||
8. | ALA4215036 | 13j | Vz | = | 6.9 | L/Kg | ALA4187438 | L.kg-1 | Mus musculus | |||
9. | ALA4215036 | 13j | beta t1/2 | = | 1 | hr | ALA4187437 | hr | Mus musculus | |||
10. | ALA4215036 | 13j | CL | = | 76 | ml/min.kg | ALA4187436 | mL.min-1.kg-1 | Mus musculus | |||
11. | ALA4215036 | 13j | Activity | 0 | ALA4187435 | Non-Toxic | Bacteroides fragilis | |||||
12. | ALA4215036 | 13j | Activity | 0 | ALA4187434 | Non-Toxic | Bifidobacterium longum | |||||
13. | ALA4215036 | 13j | Activity | 0 | ALA4187433 | Non-Toxic | Limosilactobacillus reuteri | |||||
14. | ALA4215036 | 13j | Activity | 0 | ALA4187432 | Not Active | Clostridioides difficile | |||||
15. | ALA4215036 | 13j | Stability | = | 43 | % | ALA4187431 | % | ||||
16. | ALA4215036 | 13j | Stability | = | 63 | % | ALA4187430 | % | ||||
17. | ALA4215036 | 13j | IC50 | = | 3.2 | uM | ALA4187429 | 5.50 | nM | Peptoclostridium difficile | ||
18. | ALA4215036 | 13j | IC50 | = | 0.001 | uM | ALA4187427 | 9.00 | nM | Peptoclostridium difficile | ||
19. | ALA4215036 | 13j | IC50 | = | 0.17 | uM | ALA4187428 | 6.77 | nM | Peptoclostridium difficile |