# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4215066 | 16 | Activity | 0 | ALA4186339 | Dose-dependent effect | Homo sapiens | |||||
2. | ALA4215066 | 16 | Activity | 0 | ALA4186338 | Dose-dependent effect | Homo sapiens | |||||
3. | ALA4215066 | 16 | Drug metabolism | 0 | ALA4186374 | Metabolite_Notdetected | ||||||
4. | ALA4215066 | 16 | Activity | 0 | ALA4186364 | Toxic | Mus musculus | |||||
5. | ALA4215066 | 16 | MTD | = | 25 | mg kg-1 | ALA4186358 | mg kg-1 | Mus musculus | |||
6. | ALA4215066 | 16 | Activity | 0 | ALA4186357 | Dose-dependent effect | Homo sapiens | |||||
7. | ALA4215066 | 16 | Drug metabolism | 0 | ALA4186356 | Metabolite_Notdetected | Homo sapiens | |||||
8. | ALA4215066 | 16 | Drug metabolism | 0 | ALA4186355 | Metabolite_Notdetected | Homo sapiens | |||||
9. | ALA4215066 | 16 | Drug metabolism | = | 98 | % | ALA4186354 | % | Homo sapiens | |||
10. | ALA4215066 | 16 | Drug metabolism | = | 50 | % | ALA4186353 | % | Homo sapiens | |||
11. | ALA4215066 | 16 | Drug metabolism | = | 20 | % | ALA4186352 | % | Homo sapiens | |||
12. | ALA4215066 | 16 | Drug metabolism | 0 | ALA4186351 | Tde | Homo sapiens | |||||
13. | ALA4215066 | 16 | IC50 | = | 537.7 | nM | ALA4186339 | 6.27 | nM | Homo sapiens | ||
14. | ALA4215066 | 16 | IC50 | = | 59.01 | nM | ALA4186338 | 7.23 | nM | Homo sapiens | ||
15. | ALA4215066 | 16 | IC50 | = | 75.81 | nM | ALA4186357 | 7.12 | nM | Homo sapiens |