# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4215735 | 3k | F | = | 27.8 | % | ALA4199683 | % | Rattus norvegicus | |||
2. | ALA4215735 | 3k | AUC | = | 17.4 | microg.hr/mL | ALA4199682 | ng.hr.mL-1 | Rattus norvegicus | |||
3. | ALA4215735 | 3k | AUCt | = | 17.4 | microg.hr/mL | ALA4199681 | ng.hr.mL-1 | Rattus norvegicus | |||
4. | ALA4215735 | 3k | beta t1/2 | = | 3.2 | hr | ALA4199680 | hr | Rattus norvegicus | |||
5. | ALA4215735 | 3k | Cmax | = | 3.9 | ug ml-1 | ALA4199667 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
6. | ALA4215735 | 3k | Tmax | = | 2.7 | hr | ALA4199679 | hr | Rattus norvegicus | |||
7. | ALA4215735 | 3k | Vdss | = | 0.611 | L/Kg | ALA4199678 | L.kg-1 | Rattus norvegicus | |||
8. | ALA4215735 | 3k | CL | = | 0.158 | L/hr/kg | ALA4199677 | mL.min-1.kg-1 | Rattus norvegicus | |||
9. | ALA4215735 | 3k | AUC | = | 31.8 | microg.hr/mL | ALA4199676 | ng.hr.mL-1 | Rattus norvegicus | |||
10. | ALA4215735 | 3k | AUCt | = | 31.3 | microg.hr/mL | ALA4199675 | ng.hr.mL-1 | Rattus norvegicus | |||
11. | ALA4215735 | 3k | beta t1/2 | = | 4.6 | hr | ALA4199674 | hr | Rattus norvegicus | |||
12. | ALA4215735 | 3k | Stability | = | 40.7 | % | ALA4199673 | % | ||||
13. | ALA4215735 | 3k | Stability | = | 59.6 | % | ALA4199672 | % | ||||
14. | ALA4215735 | 3k | EC50 | = | 0.004 | uM | ALA4199671 | 8.43 | nM | |||
15. | ALA4215735 | 3k | EC50 | = | 0.022 | uM | ALA4199670 | 7.66 | nM | rhinovirus A21 | ||
16. | ALA4215735 | 3k | EC50 | = | 0.066 | uM | ALA4199669 | 7.18 | nM | rhinovirus B14 | ||
17. | ALA4215735 | 3k | CC50 | = | 30.5 | uM | ALA4199668 | nM | Homo sapiens |