# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4217043 | 26 | Drug metabolism | 0 | ALA4739585 | Metabolite_Notdetected | ||||||
2. | ALA4217043 | 26 | CL | = | 45.2 | ml/min.kg | ALA4739560 | mL.min-1.kg-1 | ||||
3. | ALA4217043 | 26 | CL | = | 6.8 | ml/min.kg | ALA4739559 | mL.min-1.kg-1 | ||||
4. | ALA4217043 | 26 | Drugexcretion | = | 13.4 | % | ALA4739558 | % | ||||
5. | ALA4217043 | 26 | Vdss | = | 7 | L/Kg | ALA4739557 | L.kg-1 | ||||
6. | ALA4217043 | 26 | CL | = | 52 | ml/min.kg | ALA4739556 | mL.min-1.kg-1 | ||||
7. | ALA4217043 | 26 | Ratio | = | 1.7 | ALA4739555 | ||||||
8. | ALA4217043 | 26 | AUC | = | 1.1 | uM.hr | ALA4739554 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
9. | ALA4217043 | 26 | Vdss | = | 11.6 | L/Kg | ALA4739553 | L.kg-1 | ||||
10. | ALA4217043 | 26 | CL | = | 86.3 | ml/min.kg | ALA4739552 | mL.min-1.kg-1 | ||||
11. | ALA4217043 | 26 | t1/2 | = | 6.8 | hr | ALA4739551 | hr | ||||
12. | ALA4217043 | 26 | F | < | 5 | % | ALA4739519 | % | ||||
13. | ALA4217043 | 26 | Vdss | = | 2.7 | L/Kg | ALA4739504 | L.kg-1 | ||||
14. | ALA4217043 | 26 | CL | = | 65 | ml/min.kg | ALA4739503 | mL.min-1.kg-1 | ||||
15. | ALA4217043 | 26 | Ratio | = | 1.4 | ALA4739502 | ||||||
16. | ALA4217043 | 26 | AUC | = | 1.1 | uM.hr | ALA4739501 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
17. | ALA4217043 | 26 | Vdss | = | 3.7 | L/Kg | ALA4739500 | L.kg-1 | ||||
18. | ALA4217043 | 26 | CL | = | 88 | ml/min.kg | ALA4739499 | mL.min-1.kg-1 | ||||
19. | ALA4217043 | 26 | t1/2(app) | = | 7.4 | hr | ALA4739498 | hr | ||||
20. | ALA4217043 | 26 | IC50 | = | 12 | uM | ALA4739476 | 4.92 | nM |