Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA4217054	(S)-20a	INH	=	10	%	ALA4198246		%	Homo sapiens
2.	ALA4217054	(S)-20a	INH	=	7	%	ALA4198240		%	Homo sapiens
3.	ALA4217054	(S)-20a	INH	=	81	%	ALA4198233		%	Homo sapiens
4.	ALA4217054	(S)-20a	INH	=	39	%	ALA4198232		%	Homo sapiens
5.	ALA4217054	(S)-20a	INH	=	9.5	%	ALA4198225		%	Homo sapiens
6.	ALA4217054	(S)-20a	IC50	=	2.7	nM	ALA4198223	8.57	nM	Homo sapiens
7.	ALA4217054	(S)-20a	IC50	=	1.2	nM	ALA4198222	8.92	nM	Homo sapiens
8.	ALA4217054	(S)-20a	ED50	=	21.68	ug	ALA4198221		ug	Oryctolagus cuniculus
9.	ALA4217054	(S)-20a	Activity	>	90	%	ALA4198219		%	Oryctolagus cuniculus
10.	ALA4217054	(S)-20a	F	=	24.7	%	ALA4198216		%	Rattus norvegicus
11.	ALA4217054	(S)-20a	Vdss	=	181.3	L/Kg	ALA4198215		L.kg-1	Rattus norvegicus
12.	ALA4217054	(S)-20a	Vdss	=	72.7	L/Kg	ALA4198214		L.kg-1	Rattus norvegicus
13.	ALA4217054	(S)-20a	CL	=	19	l/hr.kg	ALA4198213		mL.min-1.kg-1	Rattus norvegicus
14.	ALA4217054	(S)-20a	CL	=	17.2	l/hr.kg	ALA4198212		mL.min-1.kg-1	Rattus norvegicus
15.	ALA4217054	(S)-20a	MRT	=	6.7	hr	ALA4198211		hr	Rattus norvegicus
16.	ALA4217054	(S)-20a	MRT	=	2.9	hr	ALA4198210		hr	Rattus norvegicus
17.	ALA4217054	(S)-20a	AUC	=	231.9	ug.hr/L	ALA4198209		ng.hr.mL-1	Rattus norvegicus
18.	ALA4217054	(S)-20a	AUC	=	125.3	ug.hr/L	ALA4198208		ng.hr.mL-1	Rattus norvegicus
19.	ALA4217054	(S)-20a	AUC	=	224.7	ug.hr/L	ALA4198207		ng.hr.mL-1	Rattus norvegicus
20.	ALA4217054	(S)-20a	AUC	=	121.1	ug.hr/L	ALA4198206		ng.hr.mL-1	Rattus norvegicus