# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4217177 | 10 | Activity | 0 | ALA4199619 | Dose-dependent effect | ||||||
2. | ALA4217177 | 10 | Activity | 0 | ALA4199618 | Dose-dependent effect | ||||||
3. | ALA4217177 | 10 | Activity | 0 | ALA4199617 | Dose-dependent effect | Leishmania infantum | |||||
4. | ALA4217177 | 10 | Activity | 0 | ALA4199616 | Dose-dependent effect | Leishmania infantum | |||||
5. | ALA4217177 | 10 | Activity | = | 57 | % | ALA4199614 | % | Leishmania infantum | |||
6. | ALA4217177 | 10 | Activity | = | 81 | % | ALA4199613 | % | Leishmania infantum | |||
7. | ALA4217177 | 10 | Activity | 0 | ALA4199612 | Toxic | Mus musculus | |||||
8. | ALA4217177 | 10 | Activity | = | 96 | % | ALA4199611 | % | Leishmania infantum | |||
9. | ALA4217177 | 10 | Activity | = | 100 | % | ALA4199610 | % | Leishmania infantum | |||
10. | ALA4217177 | 10 | Activity | 0 | ALA4199607 | Non-Toxic | Mus musculus | |||||
11. | ALA4217177 | 10 | Activity | 0 | ALA4199605 | Non-Toxic | Mus musculus | |||||
12. | ALA4217177 | 10 | Activity | 0 | ALA4199603 | Non-Toxic | Mus musculus | |||||
13. | ALA4217177 | 10 | Ratio IC50 | = | 3.22 | ALA4199602 | ||||||
14. | ALA4217177 | 10 | IC50 | = | 0.31 | uM | ALA4199601 | 6.51 | nM | Leishmania infantum | ||
15. | ALA4217177 | 10 | INH | = | 72.2 | % | ALA4199600 | % | Leishmania infantum | |||
16. | ALA4217177 | 10 | Ratio IC50 | = | 2 | ALA4199599 | ||||||
17. | ALA4217177 | 10 | Ratio IC50 | = | 1.9 | ALA4199598 | ||||||
18. | ALA4217177 | 10 | IC50 | = | 1 | uM | ALA4199597 | 6.00 | nM | Homo sapiens | ||
19. | ALA4217177 | 10 | IC50 | = | 0.52 | uM | ALA4199595 | 6.28 | nM | Leishmania infantum | ||
20. | ALA4217177 | 10 | IC50 | = | 0.51 | uM | ALA4199596 | 6.29 | nM | Leishmania tropica |