| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4217308 | 5 | F | < | 4 | % | ALA4201129 | % | Cavia porcellus | |||
| 2. | ALA4217308 | 5 | AUC | 0 | ALA4201128 | Bld | Cavia porcellus | |||||
| 3. | ALA4217308 | 5 | t1/2 | 0 | ALA4201127 | Bld | Cavia porcellus | |||||
| 4. | ALA4217308 | 5 | INH | = | 81 | % | ALA4201111 | % | Mycobacterium bovis (strain BCG / Pasteur 1173P2) | |||
| 5. | ALA4217308 | 5 | AUC | = | 4968 | ng.hr/ml | ALA4201125 | ng.hr.mL-1 | Cavia porcellus | |||
| 6. | ALA4217308 | 5 | IC50 | = | 1.3 | uM | ALA4201108 | 5.89 | nM | Mycobacterium tuberculosis | ||
| 7. | ALA4217308 | 5 | Cmax | = | 3714 | ng/ml | ALA4201123 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Cavia porcellus | ||
| 8. | ALA4217308 | 5 | IC50 | = | 2.4 | uM | ALA4201109 | 5.62 | nM | Mycobacterium tuberculosis | ||
| 9. | ALA4217308 | 5 | INH | 0 | ALA4201112 | Active | % | Mycobacterium bovis (strain BCG / Pasteur 1173P2) | ||||
| 10. | ALA4217308 | 5 | Activity | 0 | ALA4201114 | Non-Toxic | Mus musculus | |||||
| 11. | ALA4217308 | 5 | t1/2 | = | 0.7 | hr | ALA4201124 | hr | Cavia porcellus | |||
| 12. | ALA4217308 | 5 | IC50 | = | 0.92 | uM | ALA4201103 | 6.04 | nM | Mycobacterium tuberculosis | ||
| 13. | ALA4217308 | 5 | IC50 | = | 1 | uM | ALA4201110 | 6.00 | nM | Mycobacterium tuberculosis | ||
| 14. | ALA4217308 | 5 | Ratio IC50 | = | 141 | ALA4201107 | ||||||
| 15. | ALA4217308 | 5 | IC50 | = | 10.5 | uM | ALA4201106 | 4.98 | nM | Homo sapiens | ||
| 16. | ALA4217308 | 5 | IC50 | = | 127 | uM | ALA4201105 | nM | Homo sapiens | |||
| 17. | ALA4217308 | 5 | IC50 | = | 33.7 | uM | ALA4201104 | 4.47 | nM | |||
| 18. | ALA4217308 | 5 | Cmax | 0 | ALA4201126 | Bld | Cavia porcellus | |||||
| 19. | ALA4217308 | 5 | MIC | = | 0.57 | ug ml-1 | ALA4824440 | ug.mL-1 | Mycobacterium tuberculosis |
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