Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4217405	3k	IC50	=	0.17	nM	ALA4179566	9.77		nM	Homo sapiens
2.	ALA4217405	3k	IC50	=	360	nM	ALA4179567	6.44		nM	Homo sapiens
3.	ALA4217405	3k	IC50	=	100	nM	ALA4179568	7.00		nM	Homo sapiens
4.	ALA4217405	3k	IC50	=	1700	nM	ALA4179569	5.77		nM	Homo sapiens
5.	ALA4217405	3k	logD	=	2.95		ALA4179570
6.	ALA4217405	3k	Activity	=	58	%	ALA4179571			%	Homo sapiens
7.	ALA4217405	3k	Cp	=	193.6	ng/ml	ALA4179572			ng/ml
8.	ALA4217405	3k	AUC	=	118.9	ng.hr/ml	ALA4179573			ng.hr.mL-1	Rattus norvegicus
9.	ALA4217405	3k	MRT	=	2.57	hr	ALA4179574			hr	Rattus norvegicus
10.	ALA4217405	3k	Vdss	=	6631	ml/kg	ALA4179575			L.kg-1	Rattus norvegicus
11.	ALA4217405	3k	CL	=	2607	ml/hr/kg	ALA4179576			mL.min-1.kg-1	Rattus norvegicus
12.	ALA4217405	3k	Cmax	=	10.3	ng/ml	ALA4179577		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Rattus norvegicus
13.	ALA4217405	3k	AUC	=	22.9	ng.hr/ml	ALA4179578			ng.hr.mL-1	Rattus norvegicus
14.	ALA4217405	3k	MRT	=	5.69	hr	ALA4179579			hr	Rattus norvegicus
15.	ALA4217405	3k	F	=	5.8	%	ALA4179580			%	Rattus norvegicus
16.	ALA4217405	3k	MED	=	3	mg kg-1	ALA4179583			mg kg-1	Rattus norvegicus
17.	ALA4217405	3k	ED50	=	1.1	mg kg-1	ALA4179582			mg.kg-1	Rattus norvegicus
18.	ALA4217405	3k	Tmax	=	0.83	hr	ALA4179581			hr	Rattus norvegicus
19.	ALA4217405	3k	IC50	=	5100	nM	ALA4179565	5.29		nM	Homo sapiens