Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA4217579	(S)-20b	INH	=	18	%	ALA4198248		%	Homo sapiens
2.	ALA4217579	(S)-20b	INH	=	9.5	%	ALA4198239		%	Homo sapiens
3.	ALA4217579	(S)-20b	INH	=	49	%	ALA4198231		%	Homo sapiens
4.	ALA4217579	(S)-20b	INH	=	6	%	ALA4198224		%	Homo sapiens
5.	ALA4217579	(S)-20b	IC50	=	5.1	nM	ALA4198223	8.29	nM	Homo sapiens
6.	ALA4217579	(S)-20b	IC50	=	1.5	nM	ALA4198222	8.82	nM	Homo sapiens
7.	ALA4217579	(S)-20b	ED50	=	24.21	ug	ALA4198221		ug	Oryctolagus cuniculus
8.	ALA4217579	(S)-20b	Activity	>	90	%	ALA4198219		%	Oryctolagus cuniculus
9.	ALA4217579	(S)-20b	F	=	66.3	%	ALA4198216		%	Rattus norvegicus
10.	ALA4217579	(S)-20b	Vdss	=	420.9	L/Kg	ALA4198215		L.kg-1	Rattus norvegicus
11.	ALA4217579	(S)-20b	Vdss	=	124.2	L/Kg	ALA4198214		L.kg-1	Rattus norvegicus
12.	ALA4217579	(S)-20b	CL	=	33	l/hr.kg	ALA4198213		mL.min-1.kg-1	Rattus norvegicus
13.	ALA4217579	(S)-20b	CL	=	32	l/hr.kg	ALA4198212		mL.min-1.kg-1	Rattus norvegicus
14.	ALA4217579	(S)-20b	MRT	=	9.4	hr	ALA4198211		hr	Rattus norvegicus
15.	ALA4217579	(S)-20b	MRT	=	3.1	hr	ALA4198210		hr	Rattus norvegicus
16.	ALA4217579	(S)-20b	AUC	=	344.5	ug.hr/L	ALA4198209		ng.hr.mL-1	Rattus norvegicus
17.	ALA4217579	(S)-20b	AUC	=	69.3	ug.hr/L	ALA4198208		ng.hr.mL-1	Rattus norvegicus
18.	ALA4217579	(S)-20b	AUC	=	311.8	ug.hr/L	ALA4198207		ng.hr.mL-1	Rattus norvegicus
19.	ALA4217579	(S)-20b	AUC	=	67.9	ug.hr/L	ALA4198206		ng.hr.mL-1	Rattus norvegicus
20.	ALA4217579	(S)-20b	Tmax	=	1.3	hr	ALA4198205		hr	Rattus norvegicus