| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4218848 | 12; JBSNF-000265 | IC50 | = | 1533 | nM | ALA5217943 | 5.81 | nM | Homo sapiens | ||
| 2. | ALA4218848 | 12; JBSNF-000265 | INH | = | 80 | % | ALA4188619 | % | Mus musculus | |||
| 3. | ALA4218848 | 12; JBSNF-000265 | F | = | 19 | % | ALA4188618 | % | Mus musculus | |||
| 4. | ALA4218848 | 12; JBSNF-000265 | Vd | = | 1.85 | L/Kg | ALA4188617 | L.kg-1 | Mus musculus | |||
| 5. | ALA4218848 | 12; JBSNF-000265 | CL | = | 27.9 | ml/min.kg | ALA4188616 | mL.min-1.kg-1 | Mus musculus | |||
| 6. | ALA4218848 | 12; JBSNF-000265 | t1/2 | = | 0.8 | hr | ALA4188615 | hr | Mus musculus | |||
| 7. | ALA4218848 | 12; JBSNF-000265 | t1/2 | = | 1.2 | hr | ALA4188614 | hr | Mus musculus | |||
| 8. | ALA4218848 | 12; JBSNF-000265 | AUC | = | 511 | ng.hr/ml | ALA4188613 | ng.hr.mL-1 | Mus musculus | |||
| 9. | ALA4218848 | 12; JBSNF-000265 | AUC | = | 1087 | ng.hr/ml | ALA4188612 | ng.hr.mL-1 | Mus musculus | |||
| 10. | ALA4218848 | 12; JBSNF-000265 | Cmax | = | 587 | ng/ml | ALA4188611 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 11. | ALA4218848 | 12; JBSNF-000265 | Cmax | = | 1433 | ng/ml | ALA4188610 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 12. | ALA4218848 | 12; JBSNF-000265 | IC50 | > | 20 | uM | ALA4188609 | nM | Homo sapiens | |||
| 13. | ALA4218848 | 12; JBSNF-000265 | IC50 | > | 20 | uM | ALA4188608 | nM | Homo sapiens | |||
| 14. | ALA4218848 | 12; JBSNF-000265 | IC50 | > | 20 | uM | ALA4188607 | nM | Homo sapiens | |||
| 15. | ALA4218848 | 12; JBSNF-000265 | IC50 | > | 20 | uM | ALA4188606 | nM | Homo sapiens | |||
| 16. | ALA4218848 | 12; JBSNF-000265 | Ratio | = | 1.2 | ALA4188605 | ||||||
| 17. | ALA4218848 | 12; JBSNF-000265 | solubility | = | 200 | uM | ALA4188604 | nM | ||||
| 18. | ALA4218848 | 12; JBSNF-000265 | Stability | = | 69 | % | ALA4188603 | % | ||||
| 19. | ALA4218848 | 12; JBSNF-000265 | Stability | = | 97 | % | ALA4188602 | % | ||||
| 20. | ALA4218848 | 12; JBSNF-000265 | Stability | = | 85 | % | ALA4188601 | % |
The page will load shortly, Thanks for your patience!