# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4225709 | (R)-42c | CLH | < | 1 | uL/min/mg | ALA4221052 | mL.min-1.g-1 | ||||
2. | ALA4225709 | (R)-42c | CLH | = | 24 | uL/min/mg | ALA4221053 | mL.min-1.g-1 | ||||
3. | ALA4225709 | (R)-42c | IC50 | > | 10 | uM | ALA4221055 | nM | Homo sapiens | |||
4. | ALA4225709 | (R)-42c | IC50 | > | 10 | uM | ALA4221056 | nM | Homo sapiens | |||
5. | ALA4225709 | (R)-42c | Kinetic_solubility | = | 55 | ug ml-1 | ALA4221057 | ug.mL-1 | ||||
6. | ALA4225709 | (R)-42c | INH | 0 | ALA4221058 | Dose-dependent effect | % | Rattus norvegicus | ||||
7. | ALA4225709 | (R)-42c | INH | 0 | ALA4221059 | Not Active | % | Rattus norvegicus | ||||
8. | ALA4225709 | (R)-42c | Activity | 0 | ALA4221060 | Dose-dependent effect | Rattus norvegicus | |||||
9. | ALA4225709 | (R)-42c | F | = | 68 | % | ALA4221061 | % | Rattus norvegicus | |||
10. | ALA4225709 | (R)-42c | IC50 | = | 58 | nM | ALA4221048 | 7.24 | nM | Homo sapiens | ||
11. | ALA4225709 | (R)-42c | IC50 | = | 55 | nM | ALA4221049 | 7.26 | nM | Homo sapiens | ||
12. | ALA4225709 | (R)-42c | logD | = | 3.18 | ALA4221050 |