Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4241824	28h; GSK3008348	Inhibition	=	-7.36	%	ALA4303805			%	Severe acute respiratory syndrome coronavirus 2
2.	ALA4241824	28h; GSK3008348	CL	=	70	%	ALA4236947			%	Rattus norvegicus
3.	ALA4241824	28h; GSK3008348	CL	=	24	%	ALA4236995			%	Rattus norvegicus
4.	ALA4241824	28h; GSK3008348	IC50	=	1	nM	ALA4236994	9.00		nM	Homo sapiens
5.	ALA4241824	28h; GSK3008348	INH		0		ALA4236994		Dose-dependent effect	%	Homo sapiens
6.	ALA4241824	28h; GSK3008348	INH		0		ALA4236993		Active	%	Homo sapiens
7.	ALA4241824	28h; GSK3008348	t1/2	=	11	hr	ALA4236992			hr	Homo sapiens
8.	ALA4241824	28h; GSK3008348	t1/2	=	7	hr	ALA4236991			hr	Homo sapiens
9.	ALA4241824	28h; GSK3008348	Ratio	=	5.6		ALA4236984
10.	ALA4241824	28h; GSK3008348	Ratio	=	145		ALA4236983
11.	ALA4241824	28h; GSK3008348	permeability	=	20	nm/s	ALA4236982			nm/s
12.	ALA4241824	28h; GSK3008348	CLH	<	0.86	ml/min/g	ALA4236981			mL.min-1.g-1
13.	ALA4241824	28h; GSK3008348	CLH	<	1.73	ml/min/g	ALA4236980			mL.min-1.g-1
14.	ALA4241824	28h; GSK3008348	CLH	=	9.45	ml/min/g	ALA4236979			mL.min-1.g-1
15.	ALA4241824	28h; GSK3008348	CLH	=	15.3	ml/min/g	ALA4236978			mL.min-1.g-1
16.	ALA4241824	28h; GSK3008348	CLH	=	0.58	ml/min/g	ALA4236977			mL.min-1.g-1
17.	ALA4241824	28h; GSK3008348	CLH	<	0.53	ml/min/g	ALA4236976			mL.min-1.g-1
18.	ALA4241824	28h; GSK3008348	CLH	=	0.55	ml/min/g	ALA4236975			mL.min-1.g-1
19.	ALA4241824	28h; GSK3008348	CLH	=	3	ml/min/g	ALA4236974			mL.min-1.g-1
20.	ALA4241824	28h; GSK3008348	PB	=	97.3	%	ALA4236973			%