# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4244566 | 5a | Stability | > | 12 | hr | ALA4231345 | hr | ||||
2. | ALA4244566 | 5a | Ki | = | 20 | uM | ALA4231344 | 4.70 | nM | Trypanosoma brucei brucei | ||
3. | ALA4244566 | 5a | IC50 | = | 8.8 | uM | ALA4231343 | 5.06 | nM | Trypanosoma brucei brucei | ||
4. | ALA4244566 | 5a | Ki | = | 7.5 | uM | ALA4231342 | 5.12 | nM | Trypanosoma brucei brucei | ||
5. | ALA4244566 | 5a | INH | > | 50 | % | ALA4231340 | % | Trypanosoma brucei brucei | |||
6. | ALA4244566 | 5a | IC50 | = | 25 | uM | ALA4231339 | 4.60 | nM | Leishmania donovani | ||
7. | ALA4244566 | 5a | CC50 | = | 17.7 | uM | ALA4231338 | nM | Mus musculus | |||
8. | ALA4244566 | 5a | IC50 | = | 27.4 | uM | ALA4231336 | 4.56 | nM | Leishmania donovani | ||
9. | ALA4244566 | 5a | IC50 | > | 100 | uM | ALA4231334 | nM | Leishmania donovani | |||
10. | ALA4244566 | 5a | IC50 | = | 8.8 | uM | ALA4231332 | 5.06 | nM | Trypanosoma brucei gambiense | ||
11. | ALA4244566 | 5a | Ratio CC50/IC50 | = | 2 | ALA4231333 |