| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4246089 | 28h.HCl | Vd | = | 2.1 | L/Kg | ALA4375424 | L.kg-1 | ||||
| 2. | ALA4246089 | 28h.HCl | CL free | = | 150 | ml/min.kg | ALA4375420 | mL.min-1.kg-1 | ||||
| 3. | ALA4246089 | 28h.HCl | CL | = | 56 | ml/min.kg | ALA4375418 | mL.min-1.kg-1 | ||||
| 4. | ALA4246089 | 28h.HCl | Fu | = | 10.8 | % | ALA4375415 | |||||
| 5. | ALA4246089 | 28h.HCl | Fu | = | 8.3 | % | ALA4375414 | |||||
| 6. | ALA4246089 | 28h.HCl | Fu | = | 29.4 | % | ALA4375413 | |||||
| 7. | ALA4246089 | 28h.HCl | Stability | < | 0.86 | ml/min/g | ALA4375412 | ml/min/g | ||||
| 8. | ALA4246089 | 28h.HCl | Drug metabolism | = | 9.45 | ml/min/g | ALA4375411 | ml/min/g | ||||
| 9. | ALA4246089 | 28h.HCl | Kinetic_solubility | > | 0.5 | mg/ml | ALA4375409 | ug.mL-1 | ||||
| 10. | ALA4246089 | 28h.HCl | permeability | = | 89 | nm/s | ALA4375408 | nm/s | ||||
| 11. | ALA4246089 | 28h.HCl | logD | = | 2.8 | ALA4375407 | ||||||
| 12. | ALA4246089 | 28h.HCl | Ratio Ki | = | 50 | ALA4375402 | ||||||
| 13. | ALA4246089 | 28h.HCl | Ratio Ki | = | 250 | ALA4375401 | ||||||
| 14. | ALA4246089 | 28h.HCl | Ratio Ki | = | 1000 | ALA4375400 | ||||||
| 15. | ALA4246089 | 28h.HCl | Ratio Ki | = | 50 | ALA4375399 | ||||||
| 16. | ALA4246089 | 28h.HCl | pKi | = | 8.7 | ALA4375398 | 8.70 | nM | ||||
| 17. | ALA4246089 | 28h.HCl | pKi | = | 8.7 | ALA4375397 | 8.70 | nM | Homo sapiens | |||
| 18. | ALA4246089 | 28h.HCl | pIC50 | = | 8.4 | ALA4375396 | 8.40 | nM | Homo sapiens | |||
| 19. | ALA4246089 | 28h.HCl | pIC50 | = | 7.8 | ALA4375395 | 7.80 | nM | Homo sapiens | |||
| 20. | ALA4246089 | 28h.HCl | pIC50 | = | 6.9 | ALA4375394 | 6.90 | nM | Homo sapiens |
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