| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4246740 | 1; UT-800 | t1/2 | = | 9.98 | hr | ALA4236539 | hr | Mus musculus | |||
| 2. | ALA4246740 | 1; UT-800 | Activity | 0 | ALA4236488 | Active | Mycobacterium tuberculosis | |||||
| 3. | ALA4246740 | 1; UT-800 | Ratio | = | 5.44 | ALA4236538 | ||||||
| 4. | ALA4246740 | 1; UT-800 | Papp | = | 18.3 | 10'-6 cm/s | ALA4236537 | 10'-6 cm/s | ||||
| 5. | ALA4246740 | 1; UT-800 | Papp | = | 3.39 | 10'-6 cm/s | ALA4236536 | 10'-6 cm/s | ||||
| 6. | ALA4246740 | 1; UT-800 | Activity | 0 | ALA4236534 | Active | Mycobacterium tuberculosis | |||||
| 7. | ALA4246740 | 1; UT-800 | Activity | = | 100 | % | ALA4236533 | % | Mycobacterium tuberculosis | |||
| 8. | ALA4246740 | 1; UT-800 | MBC | > | 25 | ug ml-1 | ALA4236532 | ug ml-1 | Bacillus subtilis | |||
| 9. | ALA4246740 | 1; UT-800 | MIC100 | = | 25 | ug ml-1 | ALA4236531 | ug ml-1 | Bacillus subtilis | |||
| 10. | ALA4246740 | 1; UT-800 | MBC | > | 25 | ug ml-1 | ALA4236530 | ug ml-1 | Streptococcus salivarius | |||
| 11. | ALA4246740 | 1; UT-800 | MIC100 | = | 6.25 | ug ml-1 | ALA4236529 | ug ml-1 | Streptococcus salivarius | |||
| 12. | ALA4246740 | 1; UT-800 | Cmax | = | 1908 | ng/ml | ALA4236540 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 13. | ALA4246740 | 1; UT-800 | AUC | = | 993 | ng.hr/ml | ALA4236541 | ng.hr.mL-1 | Mus musculus | |||
| 14. | ALA4246740 | 1; UT-800 | AUC | = | 1046 | ng.hr/ml | ALA4236542 | ng.hr.mL-1 | Mus musculus | |||
| 15. | ALA4246740 | 1; UT-800 | t1/2 | = | 4.02 | hr | ALA4236543 | hr | Mus musculus | |||
| 16. | ALA4246740 | 1; UT-800 | Tmax | = | 0.83 | hr | ALA4236544 | hr | Mus musculus | |||
| 17. | ALA4246740 | 1; UT-800 | Cmax | = | 1344 | ng/ml | ALA4236545 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 18. | ALA4246740 | 1; UT-800 | AUC | = | 2869 | ng.hr/ml | ALA4236546 | ng.hr.mL-1 | Mus musculus | |||
| 19. | ALA4246740 | 1; UT-800 | AUC | = | 2891 | ng.hr/ml | ALA4236547 | ng.hr.mL-1 | Mus musculus | |||
| 20. | ALA4246740 | 1; UT-800 | F | = | 27.6 | % | ALA4236548 | % | Mus musculus |
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