# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4248209 | 6a | IC50 | = | 2.59 | nM | ALA4233074 | 8.59 | nM | Homo sapiens | ||
2. | ALA4248209 | 6a | IC50 | = | 4.32 | nM | ALA4233075 | 8.37 | nM | Homo sapiens | ||
3. | ALA4248209 | 6a | IC50 | = | 3.68 | nM | ALA4233076 | 8.43 | nM | Homo sapiens | ||
4. | ALA4248209 | 6a | beta t1/2 | = | 76.9 | min | ALA4233078 | hr | ||||
5. | ALA4248209 | 6a | CLH | = | 18 | ml/min.kg | ALA4233077 | mL.min-1.kg-1 | ||||
6. | ALA4248209 | 6a | beta t1/2 | = | 33.9 | min | ALA4233079 | hr | ||||
7. | ALA4248209 | 6a | CLH | = | 40.8 | ml/min.kg | ALA4233080 | mL.min-1.kg-1 | ||||
8. | ALA4248209 | 6a | beta t1/2 | = | 74.9 | min | ALA4233081 | hr | ||||
9. | ALA4248209 | 6a | CLH | = | 18.5 | ml/min.kg | ALA4233082 | mL.min-1.kg-1 | ||||
10. | ALA4248209 | 6a | beta t1/2 | = | 15.6 | min | ALA4233083 | hr | ||||
11. | ALA4248209 | 6a | CLH | = | 88.8 | ml/min.kg | ALA4233084 | mL.min-1.kg-1 | ||||
12. | ALA4248209 | 6a | beta t1/2 | = | 31.1 | min | ALA4233085 | hr | ||||
13. | ALA4248209 | 6a | CLH | = | 44.5 | ml/min.kg | ALA4233086 | mL.min-1.kg-1 | ||||
14. | ALA4248209 | 6a | beta t1/2 | = | 5.28 | hr | ALA4233087 | hr | Rattus norvegicus | |||
15. | ALA4248209 | 6a | beta t1/2 | = | 0.4 | hr | ALA4233088 | hr | Rattus norvegicus | |||
16. | ALA4248209 | 6a | AUClast | = | 883 | hr.ng/ml | ALA4233089 | ng.hr.mL-1 | Rattus norvegicus | |||
17. | ALA4248209 | 6a | AUClast | = | 591 | hr.ng/ml | ALA4233090 | ng.hr.mL-1 | Rattus norvegicus | |||
18. | ALA4248209 | 6a | MRTlast | = | 5.37 | hr | ALA4233091 | hr | Rattus norvegicus | |||
19. | ALA4248209 | 6a | MRTlast | = | 3.68 | hr | ALA4233092 | hr | Rattus norvegicus | |||
20. | ALA4248209 | 6a | F | = | 24.9 | % | ALA4233093 | % | Rattus norvegicus |