# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4278643 | 21b | Activity | 0 | ALA4264886 | Non-Toxic | Mus musculus | |||||
2. | ALA4278643 | 21b | ED99 | = | 7.8 | mg kg-1 | ALA4264885 | mg kg-1 | Mycobacterium tuberculosis | |||
3. | ALA4278643 | 21b | Activity | 0 | ALA4264884 | Dose-dependent effect | Mycobacterium tuberculosis | |||||
4. | ALA4278643 | 21b | Activity | = | 4 | deltalog10CFU | ALA4264883 | deltalog10CFU | Mycobacterium tuberculosis | |||
5. | ALA4278643 | 21b | IC50 | = | 60 | uM | ALA4264882 | 4.22 | nM | Homo sapiens | ||
6. | ALA4278643 | 21b | MIC90 | = | 6.25 | uM | ALA4264881 | nM | Mycobacterium tuberculosis | |||
7. | ALA4278643 | 21b | Stability | = | 19.4 | % | ALA4264877 | % | ||||
8. | ALA4278643 | 21b | Stability | = | 19.1 | % | ALA4264876 | % | ||||
9. | ALA4278643 | 21b | Kinetic_solubility | = | 15 | uM | ALA4264873 | nM | ||||
10. | ALA4278643 | 21b | MIC90 | = | 0.8 | uM | ALA4264872 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |