| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4279519 | 2b | Activity | 0 | ALA4268944 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
| 2. | ALA4279519 | 2b | INH | 0 | ALA4268943 | Not Active | % | Homo sapiens | ||||
| 3. | ALA4279519 | 2b | Activity | = | 56.8 | % | ALA4268942 | % | Rattus norvegicus | |||
| 4. | ALA4279519 | 2b | INH | 0 | ALA4268941 | Active | % | Mus musculus | ||||
| 5. | ALA4279519 | 2b | Activity | = | 57.4 | % | ALA4268940 | % | Mus musculus | |||
| 6. | ALA4279519 | 2b | Activity | = | 32.4 | % | ALA4268939 | % | Rattus norvegicus | |||
| 7. | ALA4279519 | 2b | Activity | 0 | ALA4268938 | Dose-dependent effect | Rattus norvegicus | |||||
| 8. | ALA4279519 | 2b | IC50 | = | 16 | nM | ALA4268937 | 7.80 | nM | Rattus norvegicus | ||
| 9. | ALA4279519 | 2b | IC50 | = | 68 | nM | ALA4268936 | 7.17 | nM | Rattus norvegicus | ||
| 10. | ALA4279519 | 2b | CLH | = | 25.3 | ml/min.kg | ALA4268935 | mL.min-1.kg-1 | ||||
| 11. | ALA4279519 | 2b | CLH | = | 9.29 | ml/min.kg | ALA4268934 | mL.min-1.kg-1 | ||||
| 12. | ALA4279519 | 2b | CLH | = | 51.42 | ml/min.kg | ALA4268933 | mL.min-1.kg-1 | ||||
| 13. | ALA4279519 | 2b | CLH | = | 9.76 | ml/min.kg | ALA4268932 | mL.min-1.kg-1 | ||||
| 14. | ALA4279519 | 2b | t1/2 | = | 2.2 | hr | ALA4268931 | hr | ||||
| 15. | ALA4279519 | 2b | t1/2 | = | 8 | hr | ALA4268930 | hr | ||||
| 16. | ALA4279519 | 2b | t1/2 | = | 1.2 | hr | ALA4268929 | hr | ||||
| 17. | ALA4279519 | 2b | t1/2 | = | 5.4 | hr | ALA4268928 | hr | ||||
| 18. | ALA4279519 | 2b | F | = | 56 | % | ALA4268927 | % | Macaca fascicularis | |||
| 19. | ALA4279519 | 2b | AUC | = | 6089 | ng.hr/ml | ALA4268926 | ng.hr.mL-1 | Macaca fascicularis | |||
| 20. | ALA4279519 | 2b | Tmax | = | 1.33 | hr | ALA4268925 | hr | Macaca fascicularis |
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