| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4280459 | 5, diastereomer 1 | INH | 0 | ALA4261878 | Dose-dependent effect | % | Rattus norvegicus | ||||
| 2. | ALA4280459 | 5, diastereomer 1 | Activity | 0 | ALA4261963 | Non-Toxic | Canis lupus familiaris | |||||
| 3. | ALA4280459 | 5, diastereomer 1 | Activity | = | 74 | % | ALA4261962 | % | Canis lupus familiaris | |||
| 4. | ALA4280459 | 5, diastereomer 1 | Activity | = | 21 | % | ALA4261961 | % | Canis lupus familiaris | |||
| 5. | ALA4280459 | 5, diastereomer 1 | fAUC | = | 1560 | ng.hr/ml | ALA4261960 | ng.hr.mL-1 | Canis lupus familiaris | |||
| 6. | ALA4280459 | 5, diastereomer 1 | fAUC | = | 149 | ng.hr/ml | ALA4261959 | ng.hr.mL-1 | Canis lupus familiaris | |||
| 7. | ALA4280459 | 5, diastereomer 1 | Ratio | = | 33 | ALA4261958 | ||||||
| 8. | ALA4280459 | 5, diastereomer 1 | Ratio | = | 3 | ALA4261957 | ||||||
| 9. | ALA4280459 | 5, diastereomer 1 | fCmax | = | 1760 | nM | ALA4261956 | nM | Canis lupus familiaris | |||
| 10. | ALA4280459 | 5, diastereomer 1 | fCmax | = | 140 | nM | ALA4261955 | nM | Canis lupus familiaris | |||
| 11. | ALA4280459 | 5, diastereomer 1 | Activity | = | 50 | % | ALA4261952 | % | Canis lupus familiaris | |||
| 12. | ALA4280459 | 5, diastereomer 1 | fAUC | = | 540 | ng.hr/ml | ALA4261928 | ng.hr.mL-1 | Canis lupus familiaris | |||
| 13. | ALA4280459 | 5, diastereomer 1 | Ratio | = | 9 | ALA4261923 | ||||||
| 14. | ALA4280459 | 5, diastereomer 1 | fCmax | = | 487 | nM | ALA4261918 | nM | Canis lupus familiaris | |||
| 15. | ALA4280459 | 5, diastereomer 1 | F | = | 32 | % | ALA4261877 | % | Canis lupus familiaris | |||
| 16. | ALA4280459 | 5, diastereomer 1 | Vdss | = | 0.58 | L/Kg | ALA4261876 | L.kg-1 | Canis lupus familiaris | |||
| 17. | ALA4280459 | 5, diastereomer 1 | CL | = | 7.3 | ml/min.kg | ALA4261875 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 18. | ALA4280459 | 5, diastereomer 1 | t1/2 | = | 3.8 | hr | ALA4261874 | hr | Canis lupus familiaris | |||
| 19. | ALA4280459 | 5, diastereomer 1 | t1/2 | = | 1.1 | hr | ALA4261873 | hr | Canis lupus familiaris | |||
| 20. | ALA4280459 | 5, diastereomer 1 | Fu | = | 0.25 | ALA4261872 |
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