| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4280900 | 1; BMS309403 | Activity | 0 | ALA4832602 | Not Active | Mus musculus | |||||
| 2. | ALA4280900 | 1; BMS309403 | Activity | 0 | ALA4832600 | Non-Toxic | Mus musculus | |||||
| 3. | ALA4280900 | 1; BMS309403 | Kd | = | 2794.5 | uM | ALA4832599 | nM | Homo sapiens | |||
| 4. | ALA4280900 | 1; BMS309403 | Kd | = | 1.67 | uM | ALA4832598 | 5.78 | nM | Homo sapiens | ||
| 5. | ALA4280900 | 1; BMS309403 | Activity | 0 | ALA4832597 | Active | Mus musculus | |||||
| 6. | ALA4280900 | 1; BMS309403 | Activity | 0 | ALA4832594 | Not Active | Mus musculus | |||||
| 7. | ALA4280900 | 1; BMS309403 | Activity | 0 | ALA4832592 | Active | Mus musculus | |||||
| 8. | ALA4280900 | 1; BMS309403 | INH | = | 38.9 | % | ALA4832589 | % | Mus musculus | |||
| 9. | ALA4280900 | 1; BMS309403 | Activity | 0 | ALA4832588 | Non-Toxic | ||||||
| 10. | ALA4280900 | 1; BMS309403 | Activity | 0 | ALA4832587 | Active | Homo sapiens | |||||
| 11. | ALA4280900 | 1; BMS309403 | Activity | 0 | ALA4832586 | Non-Toxic | Homo sapiens | |||||
| 12. | ALA4280900 | 1; BMS309403 | F | = | 7 | % | ALA4832585 | % | ||||
| 13. | ALA4280900 | 1; BMS309403 | CL | = | 44.3 | min/ml/kg | ALA4832584 | min/ml/kg | ||||
| 14. | ALA4280900 | 1; BMS309403 | AUC | = | 427 | hr.ng/ml | ALA4832583 | ng.hr.mL-1 | ||||
| 15. | ALA4280900 | 1; BMS309403 | AUC | = | 90 | hr.ng/ml | ALA4832582 | ng.hr.mL-1 | ||||
| 16. | ALA4280900 | 1; BMS309403 | Cmax | = | 151 | ng/ml | ALA4832581 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 17. | ALA4280900 | 1; BMS309403 | t1/2 | = | 1.53 | hr | ALA4832580 | hr | ||||
| 18. | ALA4280900 | 1; BMS309403 | t1/2 | = | 0.63 | hr | ALA4832579 | hr | ||||
| 19. | ALA4280900 | 1; BMS309403 | Ratio IC50 | 0 | ALA4832576 | Not Determined | ||||||
| 20. | ALA4280900 | 1; BMS309403 | Ratio IC50 | = | 15.16 | ALA4832575 |
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