# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4282514 | 20 | CL | = | 20 | ml/min.kg | ALA4256516 | mL.min-1.kg-1 | Rattus norvegicus | |||
2. | ALA4282514 | 20 | AUC/dose | = | 1301 | nmol.hr/L | ALA4256515 | nmol.hr/L | Rattus norvegicus | |||
3. | ALA4282514 | 20 | F | = | 60 | % | ALA4256514 | % | Rattus norvegicus | |||
4. | ALA4282514 | 20 | logD | = | 3.3 | ALA4256513 | ||||||
5. | ALA4282514 | 20 | log(permeability) | = | -4.5 | ALA4256512 | ||||||
6. | ALA4282514 | 20 | IC50 | < | 0.003 | uM | ALA4256508 | nM | Homo sapiens | |||
7. | ALA4282514 | 20 | IC50 | = | 0.37 | uM | ALA4256509 | 6.43 | nM | Homo sapiens | ||
8. | ALA4282514 | 20 | IC50 | = | 0.24 | uM | ALA4256510 | 6.62 | nM | Homo sapiens | ||
9. | ALA4282514 | 20 | IC50 | = | 0.8 | uM | ALA4256511 | 6.10 | nM | Homo sapiens |