| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4283244 | 3; ST8115 | Activity | 0 | ALA4274805 | Not Active | Renilla reniformis | |||||
| 2. | ALA4283244 | 3; ST8115 | Stability | 0 | ALA4274804 | Stable | % | |||||
| 3. | ALA4283244 | 3; ST8115 | Vz/F | = | 3323 | ml/kg | ALA4274803 | L.kg-1 | Mus musculus | |||
| 4. | ALA4283244 | 3; ST8115 | CL/F | = | 893 | ml/hr.kg | ALA4274802 | mL.min-1.kg-1 | Mus musculus | |||
| 5. | ALA4283244 | 3; ST8115 | beta t1/2 | = | 2.6 | hr | ALA4274801 | hr | Mus musculus | |||
| 6. | ALA4283244 | 3; ST8115 | AUC | = | 223970 | microg.hr/mL | ALA4274800 | ng.hr.mL-1 | Mus musculus | |||
| 7. | ALA4283244 | 3; ST8115 | AUClast | = | 223 | microg.hr/mL | ALA4274798 | ng.hr.mL-1 | Mus musculus | |||
| 8. | ALA4283244 | 3; ST8115 | Tlast | = | 24 | hr | ALA4274799 | hr | Mus musculus | |||
| 9. | ALA4283244 | 3; ST8115 | Clast | = | 90.7 | ug ml-1 | ALA4274797 | ug ml-1 | Mus musculus | |||
| 10. | ALA4283244 | 3; ST8115 | Tmax | = | 1 | hr | ALA4274796 | hr | Mus musculus | |||
| 11. | ALA4283244 | 3; ST8115 | Cmax | = | 17.3 | ug ml-1 | ALA4274795 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 12. | ALA4283244 | 3; ST8115 | Drug recovery | = | 66.6 | % | ALA4274793 | % | ||||
| 13. | ALA4283244 | 3; ST8115 | INH | 0 | ALA4274789 | Dose-dependent effect | % | Homo sapiens | ||||
| 14. | ALA4283244 | 3; ST8115 | INH | 0 | ALA4274788 | Dose-dependent effect | % | Homo sapiens | ||||
| 15. | ALA4283244 | 3; ST8115 | INH | = | 21 | % | ALA4274787 | % | Homo sapiens | |||
| 16. | ALA4283244 | 3; ST8115 | INH | = | 25 | % | ALA4274786 | % | Homo sapiens | |||
| 17. | ALA4283244 | 3; ST8115 | INH | = | 20 | % | ALA4274785 | % | Homo sapiens | |||
| 18. | ALA4283244 | 3; ST8115 | INH | = | 76 | % | ALA4274784 | % | Homo sapiens | |||
| 19. | ALA4283244 | 3; ST8115 | INH | = | 76 | % | ALA4274783 | % | Homo sapiens | |||
| 20. | ALA4283244 | 3; ST8115 | INH | = | 59 | % | ALA4274782 | % | Homo sapiens |
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