# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4286841 | 23 | Ratio EC50 | = | 10 | ALA4416199 | Plasmodium falciparum | |||||
2. | ALA4286841 | 23 | Ratio EC50 | = | 40 | ALA4416198 | Plasmodium falciparum | |||||
3. | ALA4286841 | 23 | Activity | 0 | ALA4416197 | Not Active | Plasmodium falciparum | |||||
4. | ALA4286841 | 23 | EC50 | = | 3.9 | uM | ALA4416194 | 5.41 | nM | Plasmodium falciparum | ||
5. | ALA4286841 | 23 | EC50 | > | 5 | uM | ALA4416193 | nM | Plasmodium falciparum | |||
6. | ALA4286841 | 23 | EC50 | = | 0.11 | uM | ALA4416192 | 6.96 | nM | Plasmodium falciparum | ||
7. | ALA4286841 | 23 | EC50 | = | 1.02 | uM | ALA4416191 | 5.99 | nM | Plasmodium falciparum | ||
8. | ALA4286841 | 23 | CLH | = | 0.49 | ml/min/g | ALA4416178 | mL.min-1.g-1 | ||||
9. | ALA4286841 | 23 | CLH | = | 6.22 | ml/min/g | ALA4416177 | mL.min-1.g-1 | ||||
10. | ALA4286841 | 23 | CLH | = | 1.32 | ml/min/g | ALA4416176 | mL.min-1.g-1 | ||||
11. | ALA4286841 | 23 | permeability | = | 3.4 | 10'-5 cm/s | ALA4416175 | 10'-5 cm/s | ||||
12. | ALA4286841 | 23 | IC50 | = | 1.34 | uM | ALA4416173 | 5.87 | nM | Homo sapiens | ||
13. | ALA4286841 | 23 | EC50 | = | 17 | uM | ALA4416174 | 4.77 | nM | Mus musculus | ||
14. | ALA4286841 | 23 | solubility | = | 311 | uM | ALA4416172 | nM | ||||
15. | ALA4286841 | 23 | logD | = | 3.2 | ALA4416171 | ||||||
16. | ALA4286841 | 23 | IC50 | = | 2 | nM | ALA4416170 | 8.70 | nM | Plasmodium falciparum | ||
17. | ALA4286841 | 23 | EC50 | = | 1.02 | uM | ALA4416169 | 5.99 | nM | Plasmodium falciparum | ||
18. | ALA4286841 | 23 | INH | 0 | ALA4267127 | Not Determined | % | Homo sapiens | ||||
19. | ALA4286841 | 23 | INH | 0 | ALA4267126 | Not Determined | % | Homo sapiens | ||||
20. | ALA4286841 | 23 | INH | < | 70 | % | ALA4267125 | % | Homo sapiens |