# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4287425 | 21h | IC50 | = | 3065 | nM | ALA5152236 | 5.51 | nM | |||
2. | ALA4287425 | 21h | IC50 | = | 5.57 | nM | ALA5152235 | 8.25 | nM | Human immunodeficiency virus 1 | ||
3. | ALA4287425 | 21h | IC50 | = | 869 | nM | ALA5152234 | 6.06 | nM | |||
4. | ALA4287425 | 21h | IC50 | = | 0.96 | nM | ALA5152233 | 9.02 | nM | |||
5. | ALA4287425 | 21h | IC50 | = | 32.18 | nM | ALA5152232 | 7.49 | nM | |||
6. | ALA4287425 | 21h | IC50 | = | 457.6 | nM | ALA5152171 | 6.34 | nM | |||
7. | ALA4287425 | 21h | IC50 | = | 0.83 | nM | ALA5152170 | 9.08 | nM | |||
8. | ALA4287425 | 21h | IC50 | = | 0.94 | nM | ALA5152169 | 9.03 | nM | |||
9. | ALA4287425 | 21h | IC50 | = | 1.88 | nM | ALA5152168 | 8.73 | nM | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | ||
10. | ALA4287425 | 21h | CLH | < | 8.6 | uL/min/kg | ALA4276536 | mL.min-1.kg-1 | ||||
11. | ALA4287425 | 21h | F | = | 10.3 | % | ALA4276554 | % | Rattus norvegicus | |||
12. | ALA4287425 | 21h | Cmax | = | 407 | ug ml-1 | ALA4276553 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
13. | ALA4287425 | 21h | Tmax | = | 0.83 | hr | ALA4276552 | hr | Rattus norvegicus | |||
14. | ALA4287425 | 21h | t1/2 | = | 3.82 | hr | ALA4276551 | hr | Rattus norvegicus | |||
15. | ALA4287425 | 21h | MRT | = | 4.05 | hr | ALA4276550 | hr | Rattus norvegicus | |||
16. | ALA4287425 | 21h | AUC | = | 1558.63 | ug/L.hr | ALA4276549 | ng.hr.mL-1 | Rattus norvegicus | |||
17. | ALA4287425 | 21h | AUCt | = | 1504.43 | ug/L.hr | ALA4276548 | ng.hr.mL-1 | Rattus norvegicus | |||
18. | ALA4287425 | 21h | Stability | = | 114.9 | % | ALA4276538 | % | ||||
19. | ALA4287425 | 21h | Stability | = | 100.6 | % | ALA4276537 | % | ||||
20. | ALA4287425 | 21h | CLH | < | 9.6 | microL/min/mg | ALA4276536 | mL.min-1.g-1 |